Metabolite Card
Formula: C17H12F3N3O4S (411.0501)
SMILES: NS(=O)(=O)C1=CC=C(C=C1)N1N=C(C=C1C1=CC=C(C=C1)C(O)=O)C(F)(F)F
Synonyms [en]
Carboxylic acid celecoxib; 4-[1-(4-sulfamoylphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzoic acid; 4-[2-(4-sulamoylphenyl)-5-(triluoromethyl)pyrazol-3-yl]benzoic acid; Celecoxib carboxylic acid; Carboxycelecoxib
Last reviewed on 2024-06-28.
Cite this Page
Carboxycelecoxib. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000055703). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Carboxycelecoxib is a metabolite of celecoxib (PMID: 10681375). Celecoxib (trade name: Celebrex) is a sulfa non-steroidal anti-inflammatory drug (NSAID) and selective COX-2 inhibitor used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation, and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis. It is marketed by Pfizer. Celecoxib is available by prescription in capsule form (Wikipedia).
DBLinks
- CAS Registry Number: 170571-01-4
- PubChem CID: 10047220
- ChEBI: 176769
- HMDB: HMDB0060571
- LipidMaps:
- KEGG:
- BioCyc:
- NCBI MeSH:
- Wikipedia:
Other DBLinks
- CAS Registry Number: 170571-01-4
- PubChem: 10047220
- ChEBI: ChEBI:176769
- HMDB: HMDB0060571
Class / Ontology
- WishartLab ClassyFire: [Pyrazoles] Pyrazoles
- ChEBI: [CHEBI:176769] Carboxylic acid celecoxib
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| PathBank:SMP0000644 | Celecoxib Metabolism Pathway |
| PathBank:SMP0000096 | Celecoxib Action Pathway |