AS-186a (BioCAD00000540773)

plant natural products microbial natural products

Metabolite Card

Formula: C21H24O6 (372.1573)
SMILES: COc1c(ccc2Oc3c(O)cc(C)cc3COC(=O)c12)[C@@H](O)CC(C)C

Synonyms [en]

PENICILLIDE; Vermixocin A; UNII-2B37T22RU5; UOWGLBYIKHMCIS-HNNXBMFYSA-N; AS-186a; 11-hydroxy-3-[(1s)-1-hydroxy-3-methylbutyl]-4-methoxy-9-methyl-5h,7h-dibenzo[b,g][1,5]dioxocin-5-one

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

AS-186a. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000540773). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

A dibenzodioxocine that is 5H,7H-dibenzo[b,g][1,5]dioxocin-5-one substituted by a hydroxy group at position 11, a (1S)-1-hydroxy-3-methylbutyl group at position 3 and a methoxy and a methyl group at positions 4 and 9 respectively. It is isolated from the culture broth of Penicillium asperosporum and acts as an acyl-CoA:cholesterol acyltransferase inhibitor." []

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 55303-92-9
  • PubChem: 124213
  • ChEBI: ChEBI:65443
  • NCBI MeSH: vermixocin A
  • Coconut NaturalProduct: CNP0241607.1
  • Coconut NaturalProduct: CNP0241607.2

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

  1. Aegiceras corniculatum [ncbi taxid: 59970]
  2. Agaricus integer [ncbi taxid: ]
  3. Agaricus silvaticus [ncbi taxid: 83517]
  4. Ajuga bracteosa [ncbi taxid: 1585251]
  5. Allium monspessulanum [ncbi taxid: ]
  6. Arbutus menziesii [ncbi taxid: 82758]
  7. Artemisia taurica [ncbi taxid: 669142]
  8. Bruguiera gymnorhiza [ncbi taxid: 39984]
  9. Buchenavia tetraphylla [ncbi taxid: ]
  10. Ceramium botryocarpum [ncbi taxid: 193554]
  11. Cereus chrysacanthus [ncbi taxid: ]
  12. Chromodoris obsoleta [ncbi taxid: ]
  13. Cinnamosma madagascariensis [ncbi taxid: 132965]
  14. Coeloseira pacifica [ncbi taxid: ]
  15. Daldinia concentrica [ncbi taxid: 42361]
  16. Echiochilon pauciflorum [ncbi taxid: 203771]
  17. Fumaria kraliki [ncbi taxid: ]
  18. Helichrysum nudifolium [ncbi taxid: 630325]
  19. Hyella caespitosa [ncbi taxid: ]
  20. Hypoxis nyasica [ncbi taxid: 2447910]
  21. Isoberlinia angolensis [ncbi taxid: 859852]
  22. Justicia trinervia [ncbi taxid: ]
  23. Lepista irina [ncbi taxid: ]
  24. Macaranga sinensis [ncbi taxid: ]
  25. Mirabilis jalapa [ncbi taxid: 3538]
  26. Otostegia fruticosa [ncbi taxid: 483855]
  27. Paranephelius uniflorus [ncbi taxid: 463613]
  28. Pardachirus pavoninus [ncbi taxid: 8286]
  29. Periploca forrestii [ncbi taxid: 2306254]
  30. Petalostemon purpureum [ncbi taxid: ]
  31. Plakinastrella clathrata [ncbi taxid: ]
  32. Podocarpus amarus [ncbi taxid: ]
  33. Potebniamyces gallicola [ncbi taxid: ]
  34. Pseudomonas chlororaphis [ncbi taxid: 587753]
  35. Ptilota pectinata [ncbi taxid: ]
  36. Rhododendron aureum [ncbi taxid: 184574]
  37. Saccharothrix mutabilis [ncbi taxid: 33921]
  38. Sipunculus nudus [ncbi taxid: 6446]
  39. Sonneratia alba [ncbi taxid: 122812]
  40. Sophora viciifolia [ncbi taxid: 1196212]
  41. Stichopus horrens [ncbi taxid: 566292]
  42. Streptomyces atratus [ncbi taxid: 1893]
  43. Streptomyces caelestis [ncbi taxid: 36816]
  44. Tephroseris integrifolia [ncbi taxid: 462580]
  45. Teucrium orientale [ncbi taxid: 1209879]
  46. Trichoderma citrinum [ncbi taxid: 1490982]
  47. Ulva prolifera [ncbi taxid: 3117]
  48. Umbilicaria cinereorufescens [ncbi taxid: 903549]
  49. Veltheimia viridifolia [ncbi taxid: ]
  50. Xylopia aethiopica [ncbi taxid: 1317910]
  51. Penicillium asperosporum [ncbi taxid: 70097]
  52. Penicillium pinophilum [ncbi taxid: ]
  53. Penicillium pinophilum + Trichoderma harzianum [ncbi taxid: ]
  54. Penicillium simplicissimum IFM53375 [ncbi taxid: ]
  55. Penicillium sp. MA-37 [ncbi taxid: ]
  56. Penicillium vermiculatum [ncbi taxid: ]

Pathway Synthetic

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