6-Pyruvoyltetrahydropterin (BioCAD00000005268)

fibroblasts placenta

Metabolite Card

Formula: C9H11N5O3 (237.0862)
SMILES: CC(=O)C(=O)C1CNC2=C(N1)C(=O)NC(N)=N2

Synonyms [en]

6-(1,2-dioxopropyl)-5,6,7,8-tetrahydropterin; Dyspropterin; 6-Pyruvoyltetrahydropterin; 6-pyruvoyl-5,6,7,8-tetrahydropterin; 1-(2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)propane-1,2-dione; 6-Pyruvoyl-tetrahydropterin

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

6-Pyruvoyltetrahydropterin. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000005268). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Dyspropterin, an intermediate formed from dihydroneopterin triphosphate in the biosynthetic pathway of tetrahydrobiopterin.

Nucleus
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 89687-39-8
  • PubChem: 135398695
  • ChEBI: ChEBI:17804
  • HMDB: HMDB0001195
  • HMDB: HMDB01195
  • KEGG: C03684
  • BioCyc: 6-PYRUVOYL-5678-TETRAHYDROPTERIN
  • NCBI MeSH: dyspropterin
  • Wikipedia: Dyspropterin
  • Metlin: METLIN_6071
  • Coconut NaturalProduct: CNP0083594.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R03984 1.5.4.1 pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing)
KEGG:R04285 1.1.1.21 6-lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2'-oxidoreductase
KEGG:R04286 4.2.3.12 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate lyase
KEGG:R08208 1.1.1.153 tetrahydrobiopterin:NADP+ oxidoreductase (6-pyruvoyltetrahydropterin-forming)
KEGG:R09990 1.1.1.325 L-threo-tetrahydrobiopterin:NADP+ oxidoreductase
KEGG:R11763 1.1.1.153 6-(1'-hydroxy-2'-oxopropyl)-tetrahydropterin:NADP+ oxidoreductase
BioCyc:4.2.3.12-RXN 4.2.3.12 DIHYDRONEOPTERIN-P3 --> 6-PYRUVOYL-5678-TETRAHYDROPTERIN + P3I + PROTON
BioCyc:RXN-15260 6-PYRUVOYL-5678-TETRAHYDROPTERIN --> CPD0-1718
BioCyc:RXN-8853 1.1.1.153 6-PYRUVOYL-5678-TETRAHYDROPTERIN + 2 NADPH + 2 PROTON --> CPD-14053 + 2 NADP
BioCyc:RXN-13030 1.1.1.325 sepiapterin reductase [(6S)-tetrahydrobiopterin-forming]
BioCyc:1.5.4.1-RXN 1.5.4.1 6-PYRUVOYL-5678-TETRAHYDROPTERIN + 2 GLUTATHIONE --> A-PYRIMIDODIAZEPINE + OXIDIZED-GLUTATHIONE + WATER
BioCyc:1.1.1.220-RXN 1.1.1.220 6-PYRUVOYL-5678-TETRAHYDROPTERIN + NADPH + PROTON --> 6-LACTOYL-5678-TETRAHYDROPTERIN + NADP
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
BioCyc:TRYPANO_PWY1V8-6195 Biopterin biosynthesis
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-8978934 Metabolism of cofactors
Reactome:R-CEL-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Reactome:R-CFA-1430728 Metabolism
Reactome:R-DRE-8978934 Metabolism of cofactors
Reactome:R-HSA-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Reactome:R-RNO-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Reactome:R-SSC-196854 Metabolism of vitamins and cofactors
Reactome:R-SSC-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Reactome:R-BTA-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Reactome:R-CFA-8978934 Metabolism of cofactors
Reactome:R-DRE-196854 Metabolism of vitamins and cofactors
Reactome:R-DRE-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Reactome:R-DDI-196854 Metabolism of vitamins and cofactors
Reactome:R-DDI-8978934 Metabolism of cofactors
Reactome:R-DME-1430728 Metabolism
Reactome:R-DME-8978934 Metabolism of cofactors
View All Pathways