5beta-Dihydrotestosterone (BioCAD00000005083)

{$topic}

Metabolite Card

Formula: C19H30O2 (290.2246)
SMILES: [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])CC(=O)CC[C@]12C

Synonyms [en]

5beta-Dihydrotestosterone; 17beta-hydroxy-5beta-androstan-3-one; 17beta-Hydroxyetiocholan-3-one; 5beta-Androstan-17beta-ol-3-one; 5-beta-Dht; Etiocholan-17-beta-ol-3-one

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

5beta-Dihydrotestosterone. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000005083). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

5beta-Dihydrotestosterone is an intermediate in Androgen and estrogen metabolism. 5beta-Dihydrotestosterone is generated from Testosterone via the enzyme 3-oxo-5beta-steroid 4-dehydrogenase (EC 1.3.99.6).

Extracellular Membrane
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 571-22-2
  • PubChem: 11302
  • ChEBI: ChEBI:2150
  • ChEBI: ChEBI:428206
  • HMDB: HMDB0006770
  • LipidMaps: LMST02020069
  • KEGG: C05293
  • BioCyc: CPD-23960
  • NCBI MeSH: Dihydrotestosterone
  • Wikipedia: 5%CE%B2-Dihydrotestosterone
  • DrugBank: DB07447
  • Metlin: METLIN_2792
  • Coconut NaturalProduct: CNP0117289.3

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R02498 1.3.1.3 5beta-dihydrotestosterone:NADP+ 4,5-oxidoreductase
Rhea:RHEA:46637 1.3.1.3 5β-dihydrotestosterone + NADP+ => testosterone + NADPH + H+
Rhea:RHEA:46638 1.3.1.3 testosterone + NADPH + H+ => 5β-dihydrotestosterone + NADP+
Rhea:RHEA:46639 1.3.1.3 5β-dihydrotestosterone + NADP+ <=> testosterone + NADPH + H+
Rhea:RHEA:69013 5β-dihydrotestosterone + NADPH + H+ => 5β-androstane-3β,17β-diol + NADP+
Rhea:RHEA:69014 5β-androstane-3β,17β-diol + NADP+ => 5β-dihydrotestosterone + NADPH + H+
Rhea:RHEA:69015 5β-dihydrotestosterone + NADPH + H+ <=> 5β-androstane-3β,17β-diol + NADP+
Rhea:RHEA:69029 5β-dihydrotestosterone + NADPH + H+ => 5β-androstane-3α,17β-diol + NADP+
Rhea:RHEA:69030 5β-androstane-3α,17β-diol + NADP+ => 5β-dihydrotestosterone + NADPH + H+
Rhea:RHEA:69031 5β-dihydrotestosterone + NADPH + H+ <=> 5β-androstane-3α,17β-diol + NADP+
View More
Organism Source

Taxonomy Source

  1. Mus musculus [ncbi taxid: 10090]

Pathway Synthetic

pathway id name
WikiPathways:WP4842 Mammalian disorder of sexual development
WikiPathways:WP5320 Male steroid hormones in cardiomyocyte energy metabolism
PathBank:SMP0120658 17-beta Hydroxysteroid Dehydrogenase III Deficiency
PathBank:SMP0120629 Aromatase Deficiency
PathBank:SMP0000068 Androgen and Estrogen Metabolism
PathBank:SMP0000356 17-beta Hydroxysteroid Dehydrogenase III Deficiency
PathBank:SMP0087405 Androgen and Estrogen Metabolism
PathBank:SMP0087489 Androgen and Estrogen Metabolism
PathBank:SMP0120848 Aromatase Deficiency
PathBank:SMP0120437 17-beta Hydroxysteroid Dehydrogenase III Deficiency
PathBank:SMP0000565 Aromatase Deficiency
PathBank:SMP0087344 Androgen and Estrogen Metabolism
PathBank:SMP0063594 Androgen and Estrogen Metabolism
PathBank:SMP0087251 Androgen and Estrogen Metabolism
View All Pathways