isovaleryl-CoA(4-) (BioCAD00000475691)

{$topic}

Metabolite Card

Formula: C26H40N7O17P3S (847.1414)
SMILES: CC(C)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP([O-])([O-])=O)n1cnc2c(N)ncnc12

Synonyms [en]

3-methylbutanoyl-CoA; isovaleryl-CoA(4-); isovaleryl-coenzyme A(4-); iso-valeryl-CoA; isovaleryl-coenzyme A; 3-methylbutanoyl-CoA(4-)

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

isovaleryl-CoA(4-). 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000475691). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

A short chain fatty acyl-CoA(4-) that is the tetraanion of isovaleryl-CoA arising from deprotonation of phosphate and diphosphate functions." []

Entity Information

DBLinks

  • CAS Registry Number:
  • PubChem CID:
  • ChEBI: 57345
  • HMDB:
  • LipidMaps:
  • KEGG:
  • BioCyc: ISOVALERYL-COA
  • NCBI MeSH:
  • Wikipedia:
Other DBLinks
  • ChEBI: ChEBI:57345
  • BioCyc: ISOVALERYL-COA

Class / Ontology

Metabolic Network
ID EC Number Name
BioCyc:RXN0-2301 1.3.8.4 ISOVALERYL-COA + ETF-Oxidized + PROTON --> 3-METHYL-CROTONYL-COA + ETF-Reduced
Rhea:RHEA:12277 1.3.8.4 3-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H+ => 3-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]
Rhea:RHEA:12278 1.3.8.4 3-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein] => 3-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H+
Rhea:RHEA:12279 1.3.8.4 3-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H+ <=> 3-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]
Rhea:RHEA:23573 2.3.1.156 3-methylbutanoyl-CoA + 3 malonyl-CoA + 3 H+ => phlorisovalerophenone + 3 CO2 + 4 CoA
Rhea:RHEA:23574 2.3.1.156 phlorisovalerophenone + 3 CO2 + 4 CoA => 3-methylbutanoyl-CoA + 3 malonyl-CoA + 3 H+
Rhea:RHEA:23575 2.3.1.156 3-methylbutanoyl-CoA + 3 malonyl-CoA + 3 H+ <=> phlorisovalerophenone + 3 CO2 + 4 CoA
Rhea:RHEA:25178 1.2.1.25 4-methyl-2-oxopentanoate + NAD+ + CoA => 3-methylbutanoyl-CoA + CO2 + NADH
Rhea:RHEA:25179 1.2.1.25 3-methylbutanoyl-CoA + CO2 + NADH => 4-methyl-2-oxopentanoate + NAD+ + CoA
Rhea:RHEA:25180 1.2.1.25 4-methyl-2-oxopentanoate + NAD+ + CoA <=> 3-methylbutanoyl-CoA + CO2 + NADH
Rhea:RHEA:37472 2.3.1.228 3-methylbutanoyl-CoA + S-adenosyl-L-methionine => N-isovaleryl-L-homoserine lactone + S-methyl-5'-thioadenosine + CoA + H+
Rhea:RHEA:37473 2.3.1.228 N-isovaleryl-L-homoserine lactone + S-methyl-5'-thioadenosine + CoA + H+ => 3-methylbutanoyl-CoA + S-adenosyl-L-methionine
Rhea:RHEA:37474 2.3.1.228 3-methylbutanoyl-CoA + S-adenosyl-L-methionine <=> N-isovaleryl-L-homoserine lactone + S-methyl-5'-thioadenosine + CoA + H+
Rhea:RHEA:42273 2.3.1.300 3-methylbutanoyl-CoA + malonyl-[ACP] + H+ => 5-methyl-3-oxohexanoyl-[ACP] + CO2 + CoA
Rhea:RHEA:42274 2.3.1.300 5-methyl-3-oxohexanoyl-[ACP] + CO2 + CoA => 3-methylbutanoyl-CoA + malonyl-[ACP] + H+
Rhea:RHEA:42275 2.3.1.300 3-methylbutanoyl-CoA + malonyl-[ACP] + H+ <=> 5-methyl-3-oxohexanoyl-[ACP] + CO2 + CoA
Rhea:RHEA:44985 3-methylbutanoyl-CoA + (R)-carnitine => O-3-methylbutanoyl-(R)-carnitine + CoA
Rhea:RHEA:44986 O-3-methylbutanoyl-(R)-carnitine + CoA => 3-methylbutanoyl-CoA + (R)-carnitine
Rhea:RHEA:44987 3-methylbutanoyl-CoA + (R)-carnitine <=> O-3-methylbutanoyl-(R)-carnitine + CoA
Rhea:RHEA:46185 3-methylbutanoate + ATP + CoA => 3-methylbutanoyl-CoA + AMP + diphosphate
View More
Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
View All Pathways