5-Androstene-3,17-dione (BioCAD00000004749)

{$topic}

Metabolite Card

Formula: C19H26O2 (286.1933)
SMILES: [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2CC(=O)CC[C@]12C

Synonyms [en]

Androst-5-ene-3,17-dione; 5-Androstene-3,17-dione; Delta(5)-Androstene-3,17-dione; delta5-Androstene-3,17-dione; J79.661A; 5-Androstenedione

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

5-Androstene-3,17-dione. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000004749). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

androst-5-ene-3,17-dione, also known as delta5-ADD or δ5-add, is classified as an androgen or an Androgen derivative. Androgens are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans. androst-5-ene-3,17-dione is considered to be practically insoluble (in water) and relatively neutral

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 571-36-8
  • PubChem: 160531
  • ChEBI: ChEBI:83865
  • HMDB: HMDB0062415
  • KEGG: C20252
  • BioCyc: CPD66-29
  • NCBI MeSH: 5-androstene-3,17-dione
  • Wikipedia: 5-Androstenedione
  • DrugBank: DB01456
  • Coconut NaturalProduct: CNP0211802.1

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R09955 5.3.3.1 5-androstene-3,17-dione delta5-delta4-isomerase
KEGG:R09957 1.1.1.51 dehydroepiandrosterone:NAD+ oxidoreductase
Rhea:RHEA:43933 1.1.1.145 3β-hydroxyandrost-5-en-17-one + NAD+ => androst-5-ene-3,17-dione + NADH + H+
Rhea:RHEA:43934 1.1.1.145 androst-5-ene-3,17-dione + NADH + H+ => 3β-hydroxyandrost-5-en-17-one + NAD+
Rhea:RHEA:43935 1.1.1.145 3β-hydroxyandrost-5-en-17-one + NAD+ <=> androst-5-ene-3,17-dione + NADH + H+
Rhea:RHEA:43937 androst-5-ene-3,17-dione => androst-4-ene-3,17-dione
Rhea:RHEA:43938 androst-4-ene-3,17-dione => androst-5-ene-3,17-dione
Rhea:RHEA:43939 androst-5-ene-3,17-dione <=> androst-4-ene-3,17-dione
BioCyc:RXN66-362 5.3.3.1 CPD66-29 --> ANDROST4ENE
BioCyc:RXN66-342 1.1.1.145 3-BETA-HYDROXYANDROST-5-EN-17-ONE + NAD<=>CPD66-29 + NADH + PROTON
View More
Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
BioCyc:HUMAN_PWY66-378 androgen biosynthesis
BioCyc:META_PWY66-378 androgen biosynthesis
View All Pathways