6-hydroxynicotinate(1-) (BioCAD00000472808)

{$topic}

Metabolite Card

Formula: C6H4NO3 (138.0191)
SMILES: Oc1ccc(cn1)C([O-])=O

Synonyms [en]

6-hydroxynicotinate; 6-hydroxynicotinate anion; 6-hydroxynicotinate(1-); 6-hydroxy-nicotinate; 6-hydroxypyridine-3-carboxylate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

6-hydroxynicotinate(1-). 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000472808). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

A monocarboxylic acid anion resulting from the deprotonation of 6-hydroxynicotinic acid; the major species at pH 7.3." []

Entity Information

DBLinks

Other DBLinks
  • ChEBI: ChEBI:57664
  • BioCyc: 6-HYDROXY-NICOTINATE

Class / Ontology

Metabolic Network
ID EC Number Name
Rhea:RHEA:12237 1.17.1.5 nicotinate + NADP+ + H2O => 6-hydroxynicotinate + NADPH + H+
Rhea:RHEA:12238 1.17.1.5 6-hydroxynicotinate + NADPH + H+ => nicotinate + NADP+ + H2O
Rhea:RHEA:12239 1.17.1.5 nicotinate + NADP+ + H2O <=> 6-hydroxynicotinate + NADPH + H+
Rhea:RHEA:17226 1.3.7.1 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized 2[4Fe-4S]-[ferredoxin] => 6-hydroxynicotinate + reduced 2[4Fe-4S]-[ferredoxin] + 2 H+
Rhea:RHEA:17227 1.3.7.1 6-hydroxynicotinate + reduced 2[4Fe-4S]-[ferredoxin] + 2 H+ => 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized 2[4Fe-4S]-[ferredoxin]
Rhea:RHEA:17228 1.3.7.1 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized 2[4Fe-4S]-[ferredoxin] <=> 6-hydroxynicotinate + reduced 2[4Fe-4S]-[ferredoxin] + 2 H+
Rhea:RHEA:22809 1.17.3.3 6-hydroxynicotinate + O2 + H2O => 2,6-dihydroxynicotinate + H2O2
Rhea:RHEA:22810 1.17.3.3 2,6-dihydroxynicotinate + H2O2 => 6-hydroxynicotinate + O2 + H2O
Rhea:RHEA:22811 1.17.3.3 6-hydroxynicotinate + O2 + H2O <=> 2,6-dihydroxynicotinate + H2O2
Rhea:RHEA:27334 1.14.13.114 6-hydroxynicotinate + NADH + O2 + 2 H+ => 2,5-dihydroxypyridine + CO2 + NAD+ + H2O
Rhea:RHEA:27335 1.14.13.114 2,5-dihydroxypyridine + CO2 + NAD+ + H2O => 6-hydroxynicotinate + NADH + O2 + 2 H+
Rhea:RHEA:27336 1.14.13.114 6-hydroxynicotinate + NADH + O2 + 2 H+ <=> 2,5-dihydroxypyridine + CO2 + NAD+ + H2O
Rhea:RHEA:27418 1.17.2.1 2 Fe(III)-[cytochrome] + nicotinate + H2O => 2 Fe(II)-[cytochrome] + 6-hydroxynicotinate + 2 H+
Rhea:RHEA:27419 1.17.2.1 2 Fe(II)-[cytochrome] + 6-hydroxynicotinate + 2 H+ => 2 Fe(III)-[cytochrome] + nicotinate + H2O
Rhea:RHEA:27420 1.17.2.1 2 Fe(III)-[cytochrome] + nicotinate + H2O <=> 2 Fe(II)-[cytochrome] + 6-hydroxynicotinate + 2 H+
BioCyc:RXN-7573 1.14.13.114 6-HYDROXY-NICOTINATE + NADH + 2 PROTON + OXYGEN-MOLECULE --> 2-5-DIHYDROXYPYRIDINE + NAD + CARBON-DIOXIDE + WATER
BioCyc:RXN-7585 1.17.3.3 6-HYDROXY-NICOTINATE + WATER + OXYGEN-MOLECULE --> CPD-6962 + HYDROGEN-PEROXIDE
BioCyc:6-HYDROXYNICOTINATE-REDUCTASE-RXN 1.3.7.1 6-HYDROXY-NICOTINATE + 2 Reduced-ferredoxins + 2 PROTON --> CPD-283 + 2 Oxidized-ferredoxins
BioCyc:RXN-11353 1.17.99.- NIACINE + WATER + Acceptor --> 6-HYDROXY-NICOTINATE + Donor-H2
BioCyc:RXN-7637 1.17.1.5 NIACINE + WATER + NADP --> 6-HYDROXY-NICOTINATE + NADPH + PROTON
View More
Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
View All Pathways