ferroheme b(2-) (BioCAD00000466005)

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Metabolite Card

Formula: C34H30FeN4O4 (614.1616)
SMILES: CC1=C(CCC([O-])=O)C2=[N+]3C1=Cc1c(C)c(C=C)c4C=C5C(C)=C(C=C)C6=[N+]5[Fe--]3(n14)n1c(=C6)c(C)c(CCC([O-])=O)c1=C2

Synonyms [en]

heme b; ferroheme b(2-); protoheme IX; protoheme; ferroprotoporphyrin IX; Heme

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

ferroheme b(2-). 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000466005). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Dicarboxylate anion of ferroheme b; major species at pH 7.3." []

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 104414-01-9
  • CAS Registry Number: 14875-96-8
  • PubChem: 25203933
  • PubChem: 53356674
  • PubChem: 644347
  • ChEBI: ChEBI:55376
  • ChEBI: ChEBI:60344
  • KEGG: C00032
  • BioCyc: CPD-11675
  • BioCyc: PROTOHEME
  • NCBI MeSH: Heme
  • Wikipedia: Heme_B
  • DrugBank: DB18267
  • MoNA: CCMSLIB00000424799
  • Metlin: METLIN_3680
  • Coconut NaturalProduct: CNP0588740.0

Class / Ontology

Metabolic Network
ID EC Number Name
BioCyc:HEMEOSYN-RXN 2.5.1.141 heme o biosynthesis
BioCyc:RXN-21407 PROTOHEME + CcmCDE-Complex + Acceptor + PROTON --> CcmCDE-Complex-Heme + Donor-H1
BioCyc:TRANS-RXN-1540 heme export
BioCyc:PROTOHEMEFERROCHELAT-RXN 4.98.1.1 PROTOHEME + 2 PROTON<=>PROTOPORPHYRIN_IX + FE+2
BioCyc:TRANS-RXN0-162 7.6.2.5 PROTOHEME + ATP + WATER<=>PROTOHEME + Pi + ADP + PROTON
Rhea:RHEA:15430 2.1.1.342 2 reduced [flavodoxin] + heme b + 2 S-adenosyl-L-methionine => anaerobilin + 2 oxidized [flavodoxin] + Fe2+ + 5'-deoxyadenosine + L-methionine + S-adenosyl-L-homocysteine
Rhea:RHEA:15431 2.1.1.342 anaerobilin + 2 oxidized [flavodoxin] + Fe2+ + 5'-deoxyadenosine + L-methionine + S-adenosyl-L-homocysteine => 2 reduced [flavodoxin] + heme b + 2 S-adenosyl-L-methionine
Rhea:RHEA:15432 2.1.1.342 2 reduced [flavodoxin] + heme b + 2 S-adenosyl-L-methionine <=> anaerobilin + 2 oxidized [flavodoxin] + Fe2+ + 5'-deoxyadenosine + L-methionine + S-adenosyl-L-homocysteine
Rhea:RHEA:19262 7.6.2.5 heme b(in) + ATP + H2O => heme b(out) + ADP + phosphate + H+
Rhea:RHEA:19263 7.6.2.5 heme b(out) + ADP + phosphate + H+ => heme b(in) + ATP + H2O
Rhea:RHEA:19264 7.6.2.5 heme b(in) + ATP + H2O <=> heme b(out) + ADP + phosphate + H+
Rhea:RHEA:21765 1.14.14.18 heme b + 3 reduced [NADPH—hemoprotein reductase] + 3 O2 => biliverdin IXα + CO + Fe2+ + 3 oxidized [NADPH—hemoprotein reductase] + 3 H2O + H+
Rhea:RHEA:21766 1.14.14.18 biliverdin IXα + CO + Fe2+ + 3 oxidized [NADPH—hemoprotein reductase] + 3 H2O + H+ => heme b + 3 reduced [NADPH—hemoprotein reductase] + 3 O2
Rhea:RHEA:21767 1.14.14.18 heme b + 3 reduced [NADPH—hemoprotein reductase] + 3 O2 <=> biliverdin IXα + CO + Fe2+ + 3 oxidized [NADPH—hemoprotein reductase] + 3 H2O + H+
Rhea:RHEA:22585 4.98.1.1 heme b + 2 H+ => protoporphyrin IX + Fe2+
Rhea:RHEA:22586 4.98.1.1 protoporphyrin IX + Fe2+ => heme b + 2 H+
Rhea:RHEA:22587 4.98.1.1 heme b + 2 H+ <=> protoporphyrin IX + Fe2+
Rhea:RHEA:22649 4.4.1.17 holo-[cytochrome c] => apo-[cytochrome c] + heme b
Rhea:RHEA:22650 4.4.1.17 apo-[cytochrome c] + heme b => holo-[cytochrome c]
Rhea:RHEA:22651 4.4.1.17 holo-[cytochrome c] <=> apo-[cytochrome c] + heme b
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Organism Source

Taxonomy Source

Pathway Synthetic

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