4-Phospho-L-aspartate (BioCAD00000004534)

urine

Metabolite Card

Formula: C4H8NO7P (213.0038)
SMILES: N[C@@H](CC(=O)OP(O)(O)=O)C(O)=O

Synonyms [en]

4-phospho-L-aspartate; L-4-Aspartyl phosphate; L-aspart-4-yl phosphate; 4-phospho-L-aspartic acid; L-beta-aspartyl dihydrogen phosphate; L-aspartyl-4-P

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

4-Phospho-L-aspartate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000004534). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

L-Aspartyl-4-phosphate belongs to the class of organic compounds known as aspartic acid and derivatives. Aspartic acid and derivatives are compounds containing an aspartic acid or a derivative thereof resulting from a reaction of aspartic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. L-Aspartyl-4-phosphate is a very strong basic compound (based on its pKa). L-Aspartyl-4-phosphate is involved in both the lysine biosynthesis I and homoserine biosynthesis pathways. L-Aspartyl-4-phosphate is produced from a reaction between L-aspartate and ATP, with ADP as a byproduct. The reaction is catalyzed by aspartate kinase. L-Aspartyl-4-phosphate reacts with NADPH to produce phosphate, L-aspartate-semialdehyde, and NADP+. Aspartate-semialdehyde dehydrogenase catalyzes this reaction.

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 22138-53-0
  • PubChem: 152441
  • PubChem: 54132310
  • ChEBI: ChEBI:15836
  • HMDB: HMDB0012250
  • KEGG: C03082
  • NCBI MeSH: beta-aspartyl phosphate
  • DrugBank: DB01857
  • RefMet: RM0042628
  • Metlin: METLIN_360
  • Coconut NaturalProduct: CNP0288689.1

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R00480 2.7.2.4 ATP:L-aspartate 4-phosphotransferase
KEGG:R02291 1.2.1.11 L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating)
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Organism Source

Taxonomy Source

  1. Arabidopsis thaliana [ncbi taxid: 3702]
  2. Escherichia coli K12 [ncbi taxid: ]

Pathway Synthetic

pathway id name
BioCyc:TRYPANO_PWY0-781 aspartate superpathway
BioCyc:TRYPANO_PWY-724 superpathway of lysine, threonine and methionine biosynthesis II
BioCyc:TRYPANO_PWY-3001 isoleucine biosynthesis I
BioCyc:CALBI_HOMOSERSYN-PWY homoserine biosynthesis
BioCyc:LEISH_HOMOSERSYN-PWY homoserine biosynthesis
BioCyc:TRYPANO_P4-PWY superpathway of lysine, threonine and methionine biosynthesis I
BioCyc:TRYPANO_THRESYN-PWY threonine biosynthesis
BioCyc:TRYPANO_DAPLYSINESYN-PWY lysine biosynthesis I
BioCyc:TRYPANO_PWY-5097 lysine biosynthesis VI
BioCyc:TRYPANO_HOMOSERSYN-PWY homoserine biosynthesis
Plant Reactome:R-OAU-2744345 Metabolism and regulation
Plant Reactome:R-OAU-2744343 Amino acid metabolism
Plant Reactome:R-OAU-1119273 Lysine biosynthesis I
Plant Reactome:R-TAE-1119419 Lysine biosynthesis VI
Plant Reactome:R-FVE-5655122 Amino acid biosynthesis
Plant Reactome:R-FVE-1119273 Lysine biosynthesis I
Plant Reactome:R-MES-2744345 Metabolism and regulation
Plant Reactome:R-MES-2744343 Amino acid metabolism
Plant Reactome:R-MES-1119295 Homoserine biosynthesis
Plant Reactome:R-MES-1119283 Lysine biosynthesis II
View All Pathways