Metabolite Card
Formula: C7H13Cl2N2O3P (274.0041)
SMILES: ClCCN(CCCl)P1(=O)NC(=O)CCO1
Synonyms [en]
4-Ketocyclophosphamide; 4-ketocyclophosphamide, (S)-isomer; 4-Ketocyclophosphamide, (R)-isomer; 4-Oxocyclophosphamide; UNII-N9DU5QVF19; 2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2$l^{5}-oxazaphosphinan-4-one
Last reviewed on 2024-06-28.
Cite this Page
4-Ketocyclophosphamide. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000004429). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
4-Ketocyclophosphamide is a metabolite of cyclophosphamide. Cyclophosphamide (trade names Endoxan, Cytoxan, Neosar, Procytox, Revimmune), also known as cytophosphane, is a nitrogen mustard alkylating agent, from the oxazophorines group. An alkylating agent adds an alkyl group (CnH2n+1) to DNA. It attaches the alkyl group to the guanine base of DNA, at the number 7 nitrogen atom of the imidazole ring. It is used to treat various types of cancer and some autoimmune disorders. (Wikipedia)
DBLinks
- CAS Registry Number: 27046-19-1
- PubChem CID: 33676
- ChEBI: 1887
- HMDB: HMDB0060686
- LipidMaps:
- KEGG: C07644
- BioCyc:
- NCBI MeSH: 4-ketocyclophosphamide
- Wikipedia:
Other DBLinks
- CAS Registry Number: 27046-19-1
- PubChem: 33676
- ChEBI: ChEBI:1887
- HMDB: HMDB0060686
- KEGG: C07644
- NCBI MeSH: 4-ketocyclophosphamide
- RefMet: RM0020586
- Metlin: METLIN_631
Class / Ontology
- WishartLab ClassyFire: [Nitrogen mustard compounds] Nitrogen mustard compounds
- RefMet: [Nitrogen mustard compounds] Nitrogen mustard compounds
- ChEBI: [CHEBI:1887] 4-Ketocyclophosphamide
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| PathBank:SMP0000447 | Cyclophosphamide Action Pathway |
| PathBank:SMP0000604 | Cyclophosphamide Metabolism Pathway |