3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate (BioCAD00000004110)

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Metabolite Card

Formula: C29H48O3 (444.3603)
SMILES: [H][C@@]12CCC([C@H](C)CCCC(C)C)[C@@]1(C)CC[C@@]1([H])C2=CC[C@]2([H])[C@]1(C)CC[C@H](O)[C@@]2(C)C(O)=O

Synonyms [en]

3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate; 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylic acid; 3b-hydroxy-4b-methyl-5a-cholest-7-ene-4a-carboxylic acid; beta-Hydroxy-4b-methyl-5a-cholest-7-ene-4a-carboxylate; 3-beta-Hydroxy-4-beta-methyl-5-alpha-cholest-7-ene-4-alpha-carboxylate; b-Hydroxy-4b-methyl-5a-cholest-7-ene-4a-carboxylate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000004110). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

3-beta-Hydroxy-4-beta-methyl-5-alpha-cholest-7-ene-4-alpha-carboxylate is a steroid biosynthesis intermediate. It is a substrate for sterol-4-alpha-carboxylate 3-dehydrogenase (EC 1.1.1.170) and participates in the following reaction: 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + NAD(P)+ = 4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NAD(P)H. It is also produced by methylsterol hydroxylase. It participates in the following reaction: 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + NAD(P)H + H+ + O2 = 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + NAD(P)+ + H2O.

Extracellular Membrane
Entity Information

DBLinks

Other DBLinks
  • PubChem: 440507
  • PubChem: 53481018
  • ChEBI: ChEBI:18134
  • HMDB: HMDB0011662
  • LipidMaps: LMST01010175
  • KEGG: C04840
  • RefMet: RM0138892
  • Coconut NaturalProduct: CNP0001914.1

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R04483 1.1.1.170 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NAD+ 3-oxidoreductase (decarboxylating)
KEGG:R05734 1.14.18.9 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde,ferrocytochrome-b5:oxygen oxidoreductase (hydroxylating)
KEGG:R07149 1.1.1.170 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NADP+ 3-oxidoreductase (decarboxylating)
KEGG:R10057 1.14.18.9 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,ferrocytochrome-b5:oxygen oxidoreductase (hydroxylating)
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Organism Source

Taxonomy Source

Pathway Synthetic

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