Metabolite Card
Formula: C9H9I2NO3 (432.8672)
SMILES: [H][C@](N)(CC1=CC(I)=C(O)C(I)=C1)C(O)=O
Synonyms [en]
3,5-Diiodo-L-tyrosine; L-Diiodotyrosine; 3,5-DIIODOTYROSINE; Diiodotyrosine; L-3,5-Diiodotyrosine; DiIY
Last reviewed on 2024-06-28.
Cite this Page
3,5-Diiodo-L-tyrosine. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000003926). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
3,5-Diiodo-L-tyrosine, also known as diiy or DIT, belongs to the class of organic compounds known as tyrosine and derivatives. Tyrosine and derivatives are compounds containing tyrosine or a derivative thereof resulting from reaction of tyrosine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. 3,5-Diiodo-L-tyrosine exists in all living organisms, ranging from bacteria to humans. In humans, 3,5-diiodo-L-tyrosine is involved in thyroid hormone synthesis. 3,5-Diiodo-L-tyrosine is a product from the iodination of monoiodotyrosine.
DBLinks
- CAS Registry Number: 300-39-0
- PubChem CID: 9305
- ChEBI: 15768
- HMDB: HMDB0003474
- LipidMaps:
- KEGG: C01060
- BioCyc:
- NCBI MeSH: Diiodotyrosine
- Wikipedia: Diiodotyrosine
Other DBLinks
- CAS Registry Number: 300-39-0
- CAS Registry Number: 300-39-0 66-02-4
- CAS Registry Number: 66-02-4
- CAS Registry Number: 881911-32-6
- PubChem: 9305
- ChEBI: ChEBI:15768
- HMDB: HMDB0003474
- KEGG: C01060
- NCBI MeSH: Diiodotyrosine
- Wikipedia: Diiodotyrosine
- DrugBank: DB03374
- RefMet: RM0012921
- MoNA: BAF_UVA_POS000029
- MoNA: BAF_UVA_POS000030
- MoNA: BAF_UVA_POS000031
- MoNA: BAF_UVA_POS000032
- MoNA: HMDB0003474_c_ms_2038
- MoNA: KO000614
- MoNA: KO000615
- MoNA: KO000616
- MoNA: KO000617
- MoNA: KO000618
- MoNA: KO002701
- MoNA: KO002702
- MoNA: KO002703
- MoNA: KO002704
- MoNA: KO002705
- MoNA: MoNA016738
- Metlin: METLIN_985
- Coconut NaturalProduct: CNP0056458.1
- Coconut NaturalProduct: CNP0056458.2
- Coconut NaturalProduct: CNP0246057.1
Class / Ontology
- WishartLab ClassyFire: [Amino acids, peptides, and analogues] Amino acids, peptides, and analogues
- RefMet: [Amino acids] Amino acids
- ChEBI: [CHEBI:15768] 3,5-diiodo-L-tyrosine
- Coconut NaturalProduct: [Aminoacids] Aminoacids
| ID | EC Number | Name |
|---|---|---|
| KEGG:R03207 | 2.6.1.24 | 3,5-diiodo-L-tyrosine:2-oxoglutarate aminotransferase |
| KEGG:R03208 | 1.11.1.8 | 2 C01060 + C00027<=>C01829 + C02218 + 2 C00001 |
| KEGG:R03953 | 1.11.1.8 | C02515 + C01060 + C00027<=>C02465 + C02218 + 2 C00001 |
| KEGG:R03973 | 1.11.1.8 | C05590 + C01060<=>C02515 + C01382 |
| KEGG:R09522 | 1.21.1.1 | L-tyrosine,iodide:NADP+ oxidoreductase (iodinating) |
| KEGG:R10059 | 1.21.1.1 | L-tyrosine,iodide:NADP+ oxidoreductase (iodinating) |
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| WikiPathways:WP3604 | Biochemical pathways: part I |