3-Hydroxykynurenine (BioCAD00000003579)

blood urine brain

Metabolite Card

Formula: C10H12N2O4 (224.0797)
SMILES: NC(CC(=O)C1=C(N)C(O)=CC=C1)C(O)=O

Synonyms [en]

3-Hydroxykynurenine; 3-Hydroxy-dl-kynurenine; 3-(3-hydroxyanthraniloyl)alanine; 2-amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid; Hydroxykinurenine; Hydroxykynurenine

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

3-Hydroxykynurenine. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000003579). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Hydroxykynurenine is a free radical generator and a bioprecursor quinolinic acid which is a endogenous excitotoxin (PMID 16697652). It is a product of enzyme kynurenine 3-monooxygenase in the tryptophan catabolism pathway (Reactome http://www.reactome.org).

Cytoplasm
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 2147-61-7
  • CAS Registry Number: 4043-91-8
  • CAS Registry Number: 484-78-6
  • PubChem: 5745
  • PubChem: 89
  • ChEBI: ChEBI:1547
  • HMDB: HMDB0000732
  • KEGG: C02794
  • NCBI MeSH: 3-hydroxykynurenine
  • Wikipedia: 3-Hydroxykynurenine
  • MoNA: CCMSLIB00000578050
  • MoNA: CCMSLIB00000578295
  • MoNA: CCMSLIB00005720492
  • MoNA: CCMSLIB00005720786
  • MoNA: EMBL-MCF_spec135072
  • MoNA: EMBL-MCF_spec135122
  • MoNA: EMBL-MCF_spec66402
  • MoNA: FiehnHILIC000075
  • MoNA: FiehnHILIC000960
  • MoNA: FIO00653
  • MoNA: FIO00654
  • MoNA: FIO00655
  • MoNA: FIO00656
  • MoNA: FIO00657
  • MoNA: KO003118
  • MoNA: KO003119
  • MoNA: KO003120
  • MoNA: KO003121
  • MoNA: KO003122
  • MoNA: KO009000
  • MoNA: KO009001
  • MoNA: KO009002
  • MoNA: KO009003
  • MoNA: KO009004
  • MoNA: KO009005
  • MoNA: MoNA002145
  • MoNA: MoNA002146
  • MoNA: MoNA002147
  • MoNA: MoNA010459
  • MoNA: MoNA010460
  • MoNA: MoNA010461
  • MoNA: MoNA010462
  • MoNA: MoNA010463
  • MoNA: MoNA010464
  • MoNA: MoNA010826
  • MoNA: MoNA010827
  • MoNA: MoNA010828
  • MoNA: MoNA010829
  • MoNA: MoNA033625
  • MoNA: MoNA033626
  • MoNA: MoNA033627
  • MoNA: MoNA035756
  • MoNA: MoNA035758
  • MoNA: MoNA035759
  • MoNA: OUF00052
  • MoNA: PR100096
  • MoNA: PR100097
  • MoNA: PR100530
  • MoNA: PS016001
  • MoNA: PT101600
  • MoNA: PT101603
  • MoNA: PT201600
  • Metlin: METLIN_365
  • Coconut NaturalProduct: CNP0152494.2

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

  1. Bombyx mori [ncbi taxid: 7091]
  2. Siegesbeckia orientalis var. pubescens [ncbi taxid: ]

Pathway Synthetic

pathway id name
BioCyc:LEISH_PWY-5651 tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
BioCyc:TRYPANO_PWY-5651 tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
BioCyc:TRYPANO_NADSYN-PWY NAD biosynthesis II (from tryptophan)
BioCyc:LEISH_NADSYN-PWY NAD biosynthesis II (from tryptophan)
WikiPathways:WP15 Selenium micronutrient network
WikiPathways:WP5044 Kynurenine pathway and links to cell senescence
WikiPathways:WP3257 Selenium micronutrient network
View All Pathways