3-Aminoisobutyric acid (BioCAD00000003377)

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Metabolite Card

Formula: C4H9NO2 (103.0633)
SMILES: CC(CN)C(O)=O

Synonyms [en]

3-aminoisobutyric acid; 3-Aminoisobutanoate; 3-Aminoisobutanoic acid; 3-Amino-2-methylpropanoate; beta-aminoisobutyric acid; dl-3-Aminoisobutyric acid

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

3-Aminoisobutyric acid. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000003377). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

3-Aminoisobutanoic acid, also known as b-aminoisobutyrate or 2-methyl-beta-alanine, belongs to the class of organic compounds known as beta amino acids and derivatives. These are amino acids having a (-NH2) group attached to the beta carbon atom. 3-Aminoisobutanoic acid is a very hydrophobic molecule, practically insoluble in water, and relatively neutral. 3-Aminoisobutanoic acid exists in all eukaryotes, ranging from yeast to humans. 3-aminoisobutanoic acid can be biosynthesized from ureidoisobutyric acid; which is mediated by the enzyme Beta-ureidopropionase. In humans, 3-aminoisobutanoic acid is involved in the metabolic disorder called the beta-ureidopropionase deficiency pathway. Beta-ureidopropionase deficiency is an inborn error of pyrimidine degradation associated with neurological abnormalities (OMIM 606673). 3-Aminoisobutanoic acid is a potentially toxic compound.

Cytoplasm
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 10569-72-9
  • CAS Registry Number: 144-90-1
  • CAS Registry Number: 4249-19-8
  • CAS Registry Number: 62-57-7
  • PubChem: 64956
  • ChEBI: ChEBI:142590
  • ChEBI: ChEBI:27389
  • HMDB: HMDB0003911
  • LipidMaps: LMFA01100054
  • KEGG: C05145
  • BioCyc: 3-AMINO-ISOBUTYRATE
  • NCBI MeSH: 3-aminoisobutyric acid
  • Wikipedia: 3-Aminoisobutyric_acid
  • RefMet: RM0153208
  • MoNA: BAF_UVA_POS000495
  • MoNA: BAF_UVA_POS000819
  • MoNA: BAF_UVA_POS000820
  • MoNA: BAF_UVA_POS000821
  • MoNA: CCMSLIB00000577917
  • MoNA: CCMSLIB00000578152
  • MoNA: CCMSLIB00005720362
  • MoNA: EMBL-MCF_spec103483
  • MoNA: FiehnHILIC001653
  • MoNA: FiehnLib000150
  • MoNA: FiehnLib000151
  • MoNA: HMDB0003911_c_ms_1138
  • MoNA: HMDB0003911_c_ms_902
  • MoNA: HMDB0003911_c_ms_963
  • MoNA: HMDB0003911_ms_ms_2349
  • MoNA: HMDB0003911_ms_ms_2350
  • MoNA: HMDB0003911_ms_ms_2351
  • MoNA: MoNA024257
  • MoNA: MoNA024314
  • MoNA: MoNA032412
  • MoNA: MoNA032414
  • MoNA: MoNA032416
  • MoNA: MoNA034457
  • MoNA: MoNA034458
  • MoNA: MoNA034459
  • MoNA: MoNA036299
  • MoNA: MoNA036300
  • MoNA: MoNA036301
  • MoNA: MoNA037289
  • MoNA: MoNA038022
  • MoNA: MoNA038477
  • MoNA: MoNA038652
  • MoNA: MoNA_0007876
  • MoNA: MoNA_0007877
  • MoNA: MoNA_0007878
  • MoNA: MoNA_0008069
  • MoNA: MoNA_0008383
  • MoNA: MoNA_0009895
  • MoNA: MoNA_0009897
  • MoNA: PM000908
  • MoNA: PR100387
  • MoNA: PR100838
  • MoNA: PT109720
  • MoNA: PT209720
  • Metlin: METLIN_480
  • Coconut NaturalProduct: CNP0291505.1

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

  1. Homo sapiens [ncbi taxid: 9606]
  2. Lunaria annua [ncbi taxid: 153659]

Pathway Synthetic

pathway id name
WikiPathways:WP4686 Leucine, isoleucine and valine metabolism
PathBank:SMP0120678 beta-Ureidopropionase Deficiency
PathBank:SMP0120750 MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)
PathBank:SMP0000178 Dihydropyrimidinase Deficiency
PathBank:SMP0120693 Dihydropyrimidinase Deficiency
PathBank:SMP0120507 UMP Synthase Deficiency (Orotic Aciduria)
PathBank:SMP0000046 Pyrimidine Metabolism
PathBank:SMP0000219 UMP Synthase Deficiency (Orotic Aciduria)
PathBank:SMP0087401 Pyrimidine Metabolism
PathBank:SMP0087473 Pyrimidine Metabolism
PathBank:SMP0120473 Dihydropyrimidinase Deficiency
PathBank:SMP0000202 MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)
PathBank:SMP0087340 Pyrimidine Metabolism
PathBank:SMP0063658 Pyrimidine Metabolism
PathBank:SMP0120727 UMP Synthase Deficiency (Orotic Aciduria)
PathBank:SMP0120458 beta-Ureidopropionase Deficiency
PathBank:SMP0120530 MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)
PathBank:SMP0000172 beta-Ureidopropionase Deficiency
PathBank:SMP0087247 Pyrimidine Metabolism
View All Pathways