(1R,2S)-1-Hydroxypropane-1,2,3-tricarboxylate (BioCAD00000000322)

blood

Metabolite Card

Formula: C6H8O7 (192.027)
SMILES: O[C@H]([C@H](CC(O)=O)C(O)=O)C(O)=O

Synonyms [en]

D-threo-Isocitric acid; (+)-threo-isocitric acid; Threo-isocitrate; (1R,2S)-1-Hydroxypropane-1,2,3-tricarboxylate; (1R,2S)-1-Hydroxypropane-1,2,3-tricarboxylic acid; DS-threo-Isocitric acid

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

(1R,2S)-1-Hydroxypropane-1,2,3-tricarboxylate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000000322). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

D-threo-Isocitric acid, also known as isocitrate or isocitrIC ACID, belongs to the class of organic compounds known as tricarboxylic acids and derivatives. These are carboxylic acids containing exactly three carboxyl groups. D-threo-Isocitric acid exists in all living species, ranging from bacteria to humans. D-threo-Isocitric acid has been detected, but not quantified in several different foods, such as citrus, fruits, common beans, green beans, and yellow wax beans.

Mitochondria Peroxisome
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 18979-21-0
  • CAS Registry Number: 6061-97-8
  • PubChem: 5318532
  • ChEBI: ChEBI:151
  • HMDB: HMDB0001874
  • KEGG: C00451
  • BioCyc: THREO-DS-ISO-CITRATE
  • MoNA: HMDB0001874_c_ms_99717
  • MoNA: HMDB0001874_c_ms_99718
  • MoNA: HMDB0001874_ms_ms_1765
  • MoNA: HMDB0001874_ms_ms_1766
  • MoNA: HMDB0001874_ms_ms_1767
  • Coconut NaturalProduct: CNP0271038.5

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R02318 5.1.2.6 (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate 1-epimerase
BioCyc:ISOCITDEH-RXN 1.1.1.42 THREO-DS-ISO-CITRATE + NADP<=>2-KETOGLUTARATE + CARBON-DIOXIDE + NADPH
BioCyc:RXN-14047 4.2.1.3 CIT<=>THREO-DS-ISO-CITRATE
BioCyc:RXN-9951 isocitrate dehydrogenase (NADP+)
BioCyc:ACONITATEHYDR-RXN cis-aconitate hydratase
BioCyc:ISOCIT-CLEAV-RXN 4.1.3.1 THREO-DS-ISO-CITRATE<=>GLYOX + SUC
BioCyc:2.3.1.126-RXN 2.3.1.126 CAFFEOYL-COA + THREO-DS-ISO-CITRATE<=>CPD-162 + CO-A
BioCyc:ISOCITRATE-DEHYDROGENASE-NAD+-RXN 1.1.1.286 THREO-DS-ISO-CITRATE + NAD --> 2-KETOGLUTARATE + CARBON-DIOXIDE + NADH
BioCyc:ISOCITRATE-EPIMERASE-RXN 5.1.2.6 THREO-DS-ISO-CITRATE<=>CPD-10748
BioCyc:R23-RXN 1.1.1.- OXALO-SUCCINATE + NADH + PROTON --> THREO-DS-ISO-CITRATE + NAD
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Organism Source

Taxonomy Source

  1. Arabidopsis thaliana [ncbi taxid: 3702]
  2. Bryophyllum calycinum [ncbi taxid: ]
  3. Escherichia coli [ncbi taxid: 562]
  4. FOOD SAKE [ncbi taxid: ]
  5. Panax ginseng [ncbi taxid: 4054]
  6. Phaseolus vulgaris [ncbi taxid: 3885]
  7. Rubus spp. [ncbi taxid: ]

Pathway Synthetic

pathway id name
PathBank:SMP0000802 TCA Cycle
PathBank:SMP0001018 TCA cycle (ubiquinol-2)
PathBank:SMP0001019 TCA cycle (ubiquinol-3)
PathBank:SMP0001020 TCA cycle (ubiquinol-4)
PathBank:SMP0001021 TCA cycle (ubiquinol-5)
PathBank:SMP0001022 TCA cycle (ubiquinol-6)
PathBank:SMP0001023 TCA cycle (ubiquinol-7)
PathBank:SMP0001024 TCA cycle (ubiquinol-8)
PathBank:SMP0001025 TCA cycle (ubiquinol-9)
PathBank:SMP0001026 TCA cycle (ubiquinol-10)
PathBank:SMP0002037 TCA cycle (ubiquinol-0)
Plant Reactome:R-OGU-1119533 TCA cycle (plant)
Plant Reactome:R-CCA-1119533 TCA cycle (plant)
Plant Reactome:R-JCU-1119533 TCA cycle (plant)
Plant Reactome:R-VAN-1119533 TCA cycle (plant)
Plant Reactome:R-SLY-1119533 TCA cycle (plant)
Plant Reactome:R-OGR-1119533 TCA cycle (plant)
Plant Reactome:R-CAR-1119533 TCA cycle (plant)
Plant Reactome:R-TPR-1119533 TCA cycle (plant)
Plant Reactome:R-OBR-1119533 TCA cycle (plant)
View All Pathways