Methylprednisolone (BioCAD00000026250)
Metabolite Card
Formula: C22H30O5 (374.2093)
SMILES: [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])C[C@H](C)C2=CC(=O)C=C[C@]12C
Synonyms [en]
methylprednisolone; delta(1)-6alpha-Methylhydrocortisone; 6alpha-Methylprednisolone; 1-Dehydro-6alpha-methylhydrocortisone; 6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione; Medrate
Last reviewed on 2024-06-28.
Cite this Page
Methylprednisolone. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000026250). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Methylprednisolone is only found in individuals that have used or taken this drug. It is a prednisolone derivative with similar anti-inflammatory action. [PubChem]Unbound glucocorticoids cross cell membranes and bind with high affinity to specific cytoplasmic receptors, modifying transcription and protein synthesis. By this mechanism, glucocorticoids can inhibit leukocyte infiltration at the site of inflammation, interfere with mediators of inflammatory response, and suppress humoral immune responses. The antiinflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.
DBLinks
- CAS Registry Number: 83-43-2
- PubChem CID: 6741
- ChEBI: 6888
- HMDB: HMDB0015094
- LipidMaps: LMST02030178
- KEGG: C16437
- BioCyc:
- NCBI MeSH: Methylprednisolone
- Wikipedia: Methylprednisolone
Other DBLinks
- CAS Registry Number: 83-43-2
- PubChem: 6741
- ChEBI: ChEBI:6888
- HMDB: HMDB0015094
- LipidMaps: LMST02030178
- KEGG: C16437
- KEGG: D00407
- NCBI MeSH: Methylprednisolone
- Wikipedia: Methylprednisolone
- DrugBank: DB00959
- MoNA: AU107601
- MoNA: AU107602
- MoNA: AU107603
- MoNA: AU107604
- MoNA: AU107605
- MoNA: AU107607
- MoNA: AU107608
- MoNA: AU107609
- MoNA: AU107610
- MoNA: AU107611
- MoNA: AU107630
- MoNA: AU107631
- MoNA: AU107632
- MoNA: AU281001
- MoNA: AU281002
- MoNA: AU281003
- MoNA: AU281004
- MoNA: AU281005
- MoNA: AU281006
- MoNA: CCMSLIB00000077142
- MoNA: CCMSLIB00000077143
- MoNA: CCMSLIB00000078262
- MoNA: EA262101
- MoNA: EA262102
- MoNA: EA262103
- MoNA: EA262104
- MoNA: EA262105
- MoNA: EA262106
- MoNA: EA262107
- MoNA: EA262108
- MoNA: EA262109
- MoNA: EA262110
- MoNA: EA262111
- MoNA: EA262112
- MoNA: EA262113
- MoNA: EA262114
- MoNA: LU090401
- MoNA: LU090402
- MoNA: LU090403
- MoNA: LU090404
- MoNA: LU090405
- MoNA: LU090406
- MoNA: PM005503
- Coconut NaturalProduct: CNP0221773.1
- Coconut NaturalProduct: CNP0363998.4
- Coconut NaturalProduct: CNP0376046.1
- Coconut NaturalProduct: CNP0376046.2
- Coconut NaturalProduct: CNP0378397.5
- Coconut NaturalProduct: CNP0418600.1
- Coconut NaturalProduct: CNP0418600.2
- Coconut NaturalProduct: CNP0418600.3
Class / Ontology
- WishartLab ClassyFire: [Hydroxysteroids] Hydroxysteroids
- LipidMaps: [C21 steroids (gluco/mineralocorticoids, progestogins) and derivatives [ST0203]] C21 steroids (gluco/mineralocorticoids, progestogins) and derivatives [ST0203]
- ChEBI: [CHEBI:6888] 6alpha-methylprednisolone
- Coconut NaturalProduct: [Pregnane steroids] Pregnane steroids
- Coconut NaturalProduct: [Cholane steroids] Cholane steroids
- Coconut NaturalProduct: [Estrane steroids] Estrane steroids
- Coconut NaturalProduct: [Benzodiazepine alkaloids] Benzodiazepine alkaloids
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| WikiPathways:WP2289 | Drug induction of bile acid pathway |
| WikiPathways:WP3253 | Drug induction of bile acid pathway |