Phosphatidylserine (BioCAD00000026015)

blood urine microbial natural products

Metabolite Card

Formula: C13H24NO10P (385.1138)
SMILES: [H][C@](N)(COP(O)(=O)OC[C@@]([H])(COC(=O)CC)OC(=O)CCC)C(O)=O

Synonyms [en]

Phosphatidylserine; (2S)-2-amino-3-[[(2R)-2-butanoyloxy-3-propanoyloxypropoxy]-hydroxyphosphoryl]oxypropanoic acid; 3-O-sn-Phosphatidyl-L-serine; N-Acetylchitosamine; Phosphatidyl-L-serine; Acetylglucosamine

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Phosphatidylserine. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000026015). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Phosphatidylserine (PS) is a phospholipid nutrient found in fish, green leafy vegetables, soybeans and rice, and is essential for the normal functioning of neuronal cell membranes and activates Protein kinase C (PKC) which has been shown to be involved in memory function. In apoptosis, phosphatidylserine is transferred to the outer leaflet of the plasma membrane. This is part of the process by which the cell is targeted for phagocytosis. PS has been shown to slow cognitive decline in animal models. PS has been investigated in a small number of double-blind placebo trials and has been shown to increase memory performance in the elderly. Because of the potentail cognitive benefits of phosphatidylserine, the substance is sold as a dietary supplement to people who believe they can benefit from an increased intake. The dietary supplement was originally processed from bovine sources however Prion disease scares in the 1990s outlawed this process, and a soy-based alternative was adopted.

Cytoplasm Extracellular Membrane
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 8002-43-5
  • PubChem: 6323481
  • ChEBI: ChEBI:18303
  • HMDB: HMDB0014291
  • HMDB: HMDB01408
  • Wikipedia: Phosphatidylserine
  • DrugBank: DB00144
  • Metlin: METLIN_6224
  • Coconut NaturalProduct: CNP0184741.1

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

  1. Streptomyces [ncbi taxid: 1883]

Pathway Synthetic

pathway id name
PathBank:SMP0001128 phospholipid biosynthesis CL(15:0cyclo/16:0/18:1(9Z)/16:0)
PathBank:SMP0001774 phospholipid biosynthesis (CL(16:1(9Z)/18:1(9Z)/16:1(9Z)/14:0))
PathBank:SMP0001994 phospholipid biosynthesis (CL(18:1(11Z)/19:0/18:1(11Z)/19:0))
PathBank:SMP0002000 phospholipid biosynthesis (CL(19:0/18:1(11Z)/14:0/14:0))
PlantCyc:SPENNELLII_PWY-5669 phosphatidylserine and phosphatidylethanolamine biosynthesis I
PlantCyc:AHYPOCHONDRIACUS_PWY-5669 phosphatidylserine and phosphatidylethanolamine biosynthesis I
PlantCyc:TOMATO_PWY-5669 phosphatidylserine and phosphatidylethanolamine biosynthesis I
PlantCyc:ASPARAGUS_PWY-5669 phosphatidylserine and phosphatidylethanolamine biosynthesis I
PlantCyc:BARLEY_PWY-5669 phosphatidylserine and phosphatidylethanolamine biosynthesis I
PlantCyc:BRACHYPODIUM_PWY-5669 phosphatidylserine and phosphatidylethanolamine biosynthesis I
PlantCyc:BRAPA_FPSC_PWY-5669 phosphatidylserine and phosphatidylethanolamine biosynthesis I
PlantCyc:BSTRICTA_PWY-5669 phosphatidylserine and phosphatidylethanolamine biosynthesis I
PlantCyc:CACUMINATA_PWY-5669 phosphatidylserine and phosphatidylethanolamine biosynthesis I
PlantCyc:CASTORBEAN_PWY-6273 phosphatidylethanolamine biosynthesis III
PlantCyc:CASTORBEAN_PWY-5669 phosphatidylserine and phosphatidylethanolamine biosynthesis I
PlantCyc:SACREDLOTUS_PWY-5669 phosphatidylserine and phosphatidylethanolamine biosynthesis I
PlantCyc:CHINESECABBAGE_PWY-5669 phosphatidylserine and phosphatidylethanolamine biosynthesis I
PlantCyc:MOSOBAMBOO_PWY-5669 phosphatidylserine and phosphatidylethanolamine biosynthesis I
PlantCyc:EGRANDIS_PWY-5669 phosphatidylserine and phosphatidylethanolamine biosynthesis I
PlantCyc:FVESCA_VESCA_PWY-5669 phosphatidylserine and phosphatidylethanolamine biosynthesis I
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