4Alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol (BioCAD00000025191)

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Metabolite Card

Formula: C28H46O2 (414.3498)
SMILES: CC(CCC=C(C)C)C1CCC2C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)[C@@H](CO)C1CC3

Synonyms [en]

4a-Hydroxymethyl-5a-cholesta-8,24-dien-3b-ol; (3~{S},4~{R},10~{S},13~{R})-17-(1,5-dimethylhex-4-enyl)-4-(hydroxymethyl)-10,13-dimethyl-2,3,4,5,6,7,11,12,14,15,16,17-dodecahydro-1~{H}-cyclopenta[a]phenanthren-3-ol; 4 alpha-hysroxymethyl-5 alpha-cholsta-8; 4 alpha-Hysroxymethyl-5 alpha-cholsta-8,24-dien-3 beta-ol; 4-alpha-Hysroxymethyl-5-alpha-cholsta-8,24-dien-3-beta-ol; 4Α-hydroxymethyl-5α-cholesta-8,24-dien-3β-ol

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

4Alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000025191). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

4Alpha-hydroxymethyl-5alpha-cholesta-8,24-dien-3beta-ol is a 3-beta-hydroxysterol that is an intermediate in cholesterol biosynthesis. It is a substrate for C-4 methyl sterol oxidase (SC4MOL) and can be generated from 4-alpha-methylzymosterol. The sequence of reactions and the types of intermediates in cholesterol biosynthesis may vary. Alternate routes exist because reduction of the carbon 24,25 double bond on the hydrocarbon side chain of the sterol ring structure by sterol delta24-reductase can occur at multiple points in the pathway, giving rise to different intermediates. These intermediates, with or without a double bond in the hydrocarbon side chain, can serve as substrates for the other enzymes in the pathway.

Extracellular Membrane
Entity Information

DBLinks

  • CAS Registry Number:
  • PubChem CID: 25202625
  • ChEBI:
  • HMDB: HMDB0012172
  • LipidMaps:
  • KEGG:
  • BioCyc:
  • NCBI MeSH:
  • Wikipedia:
Other DBLinks
  • PubChem: 25202625
  • HMDB: HMDB0012172
  • Coconut NaturalProduct: CNP0305068.2

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
BioCyc:SMAN_PWY66-341 cholesterol biosynthesis I
BioCyc:PCHR_ERGOSTEROL-SYN-PWY superpathway of ergosterol biosynthesis
BioCyc:PCHR_PWY66-4 cholesterol biosynthesis III (via desmosterol)
BioCyc:PCHR_PWY66-341 cholesterol biosynthesis I
BioCyc:THAPS_PWY66-5 superpathway of cholesterol biosynthesis
BioCyc:MOUSE_PWY66-341 cholesterol biosynthesis I
BioCyc:SMAN_PWY66-5 superpathway of cholesterol biosynthesis
BioCyc:PCHR_PWY-6074 zymosterol biosynthesis
BioCyc:THAPS_ERGOSTEROL-SYN-PWY superpathway of ergosterol biosynthesis
BioCyc:THAPS_PWY66-4 cholesterol biosynthesis III (via desmosterol)
BioCyc:MOUSE_PWY66-4 cholesterol biosynthesis III (via desmosterol)
BioCyc:SMAN_PWY66-4 cholesterol biosynthesis III (via desmosterol)
BioCyc:THAPS_PWY-6074 zymosterol biosynthesis
BioCyc:THAPS_PWY66-341 cholesterol biosynthesis I
PlantCyc:PLANT_PWY66-341 cholesterol biosynthesis I
PlantCyc:PLANT_PWY-6074 zymosterol biosynthesis
PathBank:SMP0121057 Bloch Pathway (Cholesterol Biosynthesis)
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