Tetrahydrofolyl-[Glu](n) (BioCAD00000020837)
{$topic}
Metabolite Card
Formula: C29H37N9O12 (703.2562)
SMILES: NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)NC(CCC(=O)NC(CCC(O)=O)C(O)=O)C(O)=O)C(O)=O)N2)N1
Synonyms [en]
Tetrahydrofolyl-[glu](n+1); Tetrahydropteroyl-[gamma-glu]n+1; THF-Polyglutamate; Tetrahydrofolyl-[Glu](n); THF-L-Glutamic acid; Tetrahydropteroyl-[gamma-glu]N
Last reviewed on 2024-06-28.
Cite this Page
Tetrahydrofolyl-[Glu](n). 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000020837). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Tetrahydrofolyl-[Glu](n) is involved in the folate biosynthesis pathway. Tetrahydrofolyl-[Glu](n) can be reversibly converted into Tetrahydrofolyl-[Glu](2) by folylpolyglutamate synthase [EC:6.3.2.17]. Tetrahydrofolyl-[Glu](n) can be irreversibly converted into tetrahydrofolate by gamma-glutamyl hydrolase [EC:3.4.19.9]. Sample structure image shows the case when n=3.
DBLinks
- CAS Registry Number:
- PubChem CID: 45479706
- ChEBI: 27650
- HMDB: HMDB0006826
- LipidMaps:
- KEGG: C03541
- BioCyc:
- NCBI MeSH:
- Wikipedia:
Other DBLinks
- PubChem: 45479706
- ChEBI: ChEBI:27650
- HMDB: HMDB0006826
- KEGG: C03541
Class / Ontology
- WishartLab ClassyFire: [Pterins and derivatives] Pterins and derivatives
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| PathBank:SMP0120742 | Methylenetetrahydrofolate Reductase Deficiency (MTHFRD) |
| PathBank:SMP0000432 | Methotrexate Action Pathway |
| PathBank:SMP0000543 | Methylenetetrahydrofolate Reductase Deficiency (MTHFRD) |
| PathBank:SMP0087196 | Folate Metabolism |
| PathBank:SMP0120656 | Folate Malabsorption, Hereditary |
| PathBank:SMP0087380 | Folate Metabolism |
| PathBank:SMP0120875 | Folate Malabsorption, Hereditary |
| PathBank:SMP0120522 | Methylenetetrahydrofolate Reductase Deficiency (MTHFRD) |
| PathBank:SMP0000053 | Folate Metabolism |
| PathBank:SMP0000724 | Folate Malabsorption, Hereditary |
| PathBank:SMP0000801 | Folate Metabolism |
| PathBank:SMP0087295 | Folate Metabolism |
| PathBank:SMP0087435 | Folate Metabolism |