(10E,12Z)-Octadecadienoic acid (BioCAD00000020520)
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Metabolite Card
Formula: C18H32O2 (280.2402)
SMILES: CCCCC\C=C/C=C/CCCCCCCCC(O)=O
Synonyms [en]
(10E,12Z)-Octadecadienoic acid; 10E,12Z-Octadecadienoic acid; 10-trans-12-cis-conjugated linoleic acid; (e,Z)-Octadeca-10,12-dienoic acid; 10-trans-12-cis-Linoleic acid; (10E,12Z)-octadeca-10,12-dienoic acid
Last reviewed on 2024-06-28.
Cite this Page
(10E,12Z)-Octadecadienoic acid. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000020520). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Conjugated linoleic acid (CLA) is a collective term for a mixture of positional and geometric isomers of linoleic acid (18:2) in which the two double bonds are conjugated. CLA has been suggested to have effects on human health, including effects on body composition, blood lipids, liver metabolism, insulin sensitivity and immune function, with mixed results. Some reported data suggest that the effects of the substance may be isomer dependent and that cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acids have opposing effects, the later (trans-10,cis-12 CLA) having a relative detrimental effect on blood lipids. (PMID 16477173).
DBLinks
- CAS Registry Number: 2420-56-6
- PubChem CID: 5282800
- ChEBI: 44526
- HMDB: HMDB0005048
- LipidMaps: LMFA01030125
- KEGG:
- BioCyc:
- NCBI MeSH: trans-10,cis-12-conjugated linoleic acid
- Wikipedia:
Other DBLinks
- CAS Registry Number: 2420-56-6
- PubChem: 5282800
- PubChem: 5351472
- ChEBI: ChEBI:44526
- HMDB: HMDB0005048
- HMDB: HMDB05048
- LipidMaps: LMFA01030125
- LipidMaps: LMFA02000307
- NCBI MeSH: trans-10,cis-12-conjugated linoleic acid
- DrugBank: DB04746
- RefMet: RM0202138
- MoNA: MetaboBASE1003
- MoNA: MetaboBASE1004
- MoNA: MetaboBASE1005
- MoNA: MetaboBASE1006
- MoNA: MetaboBASE1007
- Metlin: METLIN_34801
- Metlin: METLIN_73836
Class / Ontology
- WishartLab ClassyFire: [Lineolic acids and derivatives] Lineolic acids and derivatives
- RefMet: [Unsaturated FA] Unsaturated FA
- LipidMaps: [Unsaturated fatty acids [FA0103]] Unsaturated fatty acids [FA0103]
- LipidMaps: [Other Octadecanoids [FA0200]] Other Octadecanoids [FA0200]
- ChEBI: [CHEBI:44526] (10E,12Z)-octadecadienoic acid
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| WikiPathways:WP5324 | Octadecanoid formation from linoleic acid |