Vincamine (BioCAD00000019357)

plant natural products microbial natural products

Metabolite Card

Formula: C21H26N2O3 (354.1943)
SMILES: [H][C@]12N3CCC[C@@]1(CC)C[C@](O)(C(=O)OC)n1c2c(CC3)c2ccccc12

Synonyms [en]

vincamine; (+)-Vincamine; Methyl vincaminate; Vincamidol; Vincamin; Pervincamine

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Vincamine. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000019357). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Vincamine is a vinca alkaloid, an alkaloid ester, an organic heteropentacyclic compound, a methyl ester and a hemiaminal. It has a role as an antihypertensive agent, a vasodilator agent and a metabolite. It is functionally related to an eburnamenine. Vincamine is a monoterpenoid indole alkaloid obtained from the leaves of *Vinca minor* with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow. Vincamine is a natural product found in Vinca difformis, Vinca major, and other organisms with data available. A major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorders.

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 1617-90-9
  • CAS Registry Number: 2122-39-6
  • CAS Registry Number: 6835-99-0
  • CAS Registry Number: 83508-82-1
  • PubChem: 15376
  • PubChem: 5668
  • PubChem: 6432151
  • ChEBI: ChEBI:9985
  • KEGG: C09251
  • KEGG: D08677
  • NCBI MeSH: Vincamine
  • Wikipedia: Vincamine
  • DrugBank: DB13374
  • MoNA: Alkaloids000148
  • MoNA: BML00348
  • MoNA: BML82335
  • MoNA: BML82337
  • MoNA: CCMSLIB00004680076
  • MoNA: LU016801
  • MoNA: LU016802
  • MoNA: LU016803
  • MoNA: LU016804
  • MoNA: LU016805
  • MoNA: LU016806
  • MoNA: NA002551
  • MoNA: NA002552
  • MoNA: NA002553
  • MoNA: NA002554
  • MoNA: NA002555
  • MoNA: NA002944
  • MoNA: NA002945
  • MoNA: NA002946
  • MoNA: NA002947
  • MoNA: NA002948
  • MoNA: NA003319
  • MoNA: NA003320
  • MoNA: NA003321
  • MoNA: NA003322
  • MoNA: NA003323
  • MoNA: NA003689
  • MoNA: NA003690
  • MoNA: NA003691
  • MoNA: NA003692
  • MoNA: NA003693
  • MoNA: PR310611
  • MoNA: RIKENPlaSMA001542
  • MoNA: RIKENPlaSMA001546
  • MoNA: RIKENPlaSMA001550
  • MoNA: RIKENPlaSMA001554
  • MoNA: RIKENPlaSMA001557
  • MoNA: RIKENPlaSMA001561
  • MoNA: RIKENPlaSMA001565
  • MoNA: RIKENPlaSMA001569
  • MoNA: RIKENPlaSMA001573
  • MoNA: RIKENPlaSMA001577
  • MoNA: RIKENPlaSMA001581
  • MoNA: RIKENPlaSMA001585
  • MoNA: TOF_alkaloids_pos000118
  • MoNA: VF-NPL-LTQ006451
  • MoNA: VF-NPL-LTQ006452
  • MoNA: VF-NPL-LTQ006453
  • MoNA: VF-NPL-LTQ006454
  • MoNA: VF-NPL-QEHF003394
  • MoNA: VF-NPL-QEHF003395
  • MoNA: VF-NPL-QEHF003396
  • MoNA: VF-NPL-QEHF003397
  • MoNA: VF-NPL-QEHF003398
  • MoNA: VF-NPL-QEHF003399
  • MoNA: VF-NPL-QEHF003400
  • MoNA: VF-NPL-QEHF003401
  • MoNA: VF-NPL-QEHF003402
  • MoNA: WA002422
  • MoNA: WA002423
  • MoNA: WA002424
  • MoNA: WA002425
  • MoNA: WA002426
  • Metlin: METLIN_44262
  • Coconut NaturalProduct: CNP0213228.1
  • Coconut NaturalProduct: CNP0213228.2
  • Coconut NaturalProduct: CNP0213228.4
  • Coconut NaturalProduct: CNP0213228.5
  • Coconut NaturalProduct: CNP0213228.6
  • Coconut NaturalProduct: CNP0213228.7
  • Coconut NaturalProduct: CNP0258411.0
  • Coconut NaturalProduct: CNP0391745.0
  • Coconut NaturalProduct: CNP0393274.0

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

  1. Abrus pulchellus subsp. cantoniensis [ncbi taxid: 858909]
  2. Alstonia spatulata [ncbi taxid: ]
  3. Bambusa chungii [ncbi taxid: 318047]
  4. Brugmansia arborea [ncbi taxid: 41689]
  5. Catharanthus roseus [ncbi taxid: 4058]
  6. Diospyros tricolor [ncbi taxid: ]
  7. Drymonia macrophylla [ncbi taxid: 213363]
  8. Eriostemon deserti [ncbi taxid: ]
  9. Gentiana pyrenaica [ncbi taxid: 49955]
  10. Gloxinia erinoides [ncbi taxid: 63546]
  11. Gynura elliptica [ncbi taxid: ]
  12. Ostrinia nubilalis [ncbi taxid: 29057]
  13. Relicina connivens [ncbi taxid: ]
  14. Ruta oreojasme [ncbi taxid: 452793]
  15. Streptomyces roseoviolaceus [ncbi taxid: 67360]
  16. Vinca erecta Rgl.et Schmalh. [ncbi taxid: ]
  17. Vinca herbacea Waldst.et Kit. [ncbi taxid: ]
  18. Vinca major [ncbi taxid: 185238]
  19. Vinca major L. [ncbi taxid: ]
  20. Vinca minor [ncbi taxid: 60093]
  21. Vinca minor L. [ncbi taxid: ]
  22. Alstonia spatulata [ncbi taxid: ]
  23. Tabernaemontana rigida [ncbi taxid: ]
  24. Tabernaemontana rigida (Miers) Leeuwenberg [ncbi taxid: ]
  25. Vinca minor [ncbi taxid: 60093]
  26. Vinca minor L. [ncbi taxid: ]
  27. Tabernaemontana rigida (Miers) Leeuwenberg [ncbi taxid: ]
  28. Abrus pulchellus subsp. cantoniensis [ncbi taxid: 858909]
  29. Bambusa chungii [ncbi taxid: 318047]
  30. Brugmansia arborea [ncbi taxid: 41689]
  31. Diospyros tricolor [ncbi taxid: ]
  32. Drymonia macrophylla [ncbi taxid: 213363]
  33. Eriostemon deserti [ncbi taxid: ]
  34. Gentiana pyrenaica [ncbi taxid: 49955]
  35. Gloxinia erinoides [ncbi taxid: 63546]
  36. Gynura elliptica [ncbi taxid: ]
  37. Ostrinia nubilalis [ncbi taxid: 29057]
  38. Relicina connivens [ncbi taxid: ]
  39. Ruta oreojasme [ncbi taxid: 452793]
  40. Streptomyces roseoviolaceus [ncbi taxid: 67360]
  41. Vinca major [ncbi taxid: 185238]

Pathway Synthetic

pathway id name
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