Scopolin (BioCAD00000017619)

plant natural products microbial natural products

Metabolite Card

Formula: C16H18O9 (354.0951)
SMILES: COc1cc2ccc(=O)oc2cc1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

Synonyms [en]

Scopolin; 7-(beta-D-glucopyranosoyloxy)-6-methoxy-2H-1-benzopyran-2-one; 6-methoxy-2-oxo-2H-chromen-7-yl beta-D-glucopyranoside; 7beta-D-Glucopyranosyloxy-6-methoxycumarin; 7-(beta-D-GLUCOPYRANOSYLOXY)-6-METHOXYCOUMARIN; 6-METHOXYCOUMARIN 7-O-beta-D-GLUCOSIDE

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Scopolin. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000017619). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

A member of the class of coumarins that is scopoletin attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage." []

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 531-44-2
  • PubChem: 439514
  • ChEBI: ChEBI:16065
  • KEGG: C01527
  • BioCyc: SCOPOLIN
  • NCBI MeSH: scopolin
  • Wikipedia: Scopolin
  • MoNA: ......
  • MoNA: CCMSLIB00005463762
  • MoNA: PM018131
  • Metlin: METLIN_64175
  • Coconut NaturalProduct: CNP0344517.1
  • Coconut NaturalProduct: CNP0344517.4

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R03594 2.4.1.128 UDPglucose:scopoletin O-beta-D-glucosyltransferase
Rhea:RHEA:20454 2.4.1.128 scopoletin + UDP-α-D-glucose => scopolin + UDP + H+
Rhea:RHEA:20455 2.4.1.128 scopolin + UDP + H+ => scopoletin + UDP-α-D-glucose
Rhea:RHEA:20456 2.4.1.128 scopoletin + UDP-α-D-glucose <=> scopolin + UDP + H+
BioCyc:SCOPOLETIN-GLUCOSYLTRANSFERASE-RXN 2.4.1.128 CPD-12575 + SCOPOLETIN --> PROTON + SCOPOLIN + UDP
BioCyc:RXN-14179 3.2.1.21 SCOPOLIN + WATER --> SCOPOLETIN + Glucopyranose
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Organism Source

Taxonomy Source

  1. Acacia cambagei [ncbi taxid: 1173637]
  2. Acer saccharum [ncbi taxid: 4024]
  3. Achillea roseoalba [ncbi taxid: 282763]
  4. Acinetobacter baumannii [ncbi taxid: 470]
  5. Acinetobacter calcoaceticus [ncbi taxid: 471]
  6. Aconitum brevicalcaratum [ncbi taxid: 1905853]
  7. Aconitum zuccarini [ncbi taxid: ]
  8. Acritopappus confertus [ncbi taxid: 1744986]
  9. Aesculus pavia L. [ncbi taxid: ]
  10. Agave rigidissima [ncbi taxid: ]
  11. Aka coralliphagum [ncbi taxid: ]
  12. Althaea officinalis [ncbi taxid: 145745]
  13. Ammodendron conollyi [ncbi taxid: 449078]
  14. Androcymbium palaestinum [ncbi taxid: 208217]
  15. Angelica dahurica [ncbi taxid: 48101]
  16. Aniba duckei [ncbi taxid: ]
  17. Ankistrodesmus braunii [ncbi taxid: ]
  18. Anthemis spp. [ncbi taxid: ]
  19. Aphanoascus terreus [ncbi taxid: ]
  20. Aplidiopsis confluata [ncbi taxid: ]
  21. Arabidopsis thaliana [ncbi taxid: 3702]
  22. Aralidium pinnatifidum [ncbi taxid: 48205]
  23. Arnica viscosa [ncbi taxid: 436215]
  24. Artemisia annua [ncbi taxid: 35608]
  25. Artemisia argyi [ncbi taxid: 259893]
  26. Artemisia capillaris [ncbi taxid: 265783]
  27. Artemisia iwayomogi [ncbi taxid: 265784]
  28. Artemisia minor [ncbi taxid: 1227633]
  29. Artemisia montana [ncbi taxid: 669134]
  30. Artemisia princeps [ncbi taxid: 223870]
  31. Artemisia spp. [ncbi taxid: ]
  32. Aspergillus aculeatus [ncbi taxid: 5053]
  33. Aster alpinus [ncbi taxid: 669631]
  34. Astragalus brachycarpus [ncbi taxid: 1264805]
  35. Astragalus falcatus [ncbi taxid: 47038]
  36. Athanasia dregeana [ncbi taxid: ]
  37. Baccharis solieri [ncbi taxid: ]
  38. Bacillus thuringiensis [ncbi taxid: 1428]
  39. Banisteriopsis caapi [ncbi taxid: 577683]
  40. Baptisia arachnifera [ncbi taxid: 3120269]
  41. Baptisia bracteata [ncbi taxid: 313912]
  42. Baptisia calycosa [ncbi taxid: 1969220]
  43. Baptisia cinerea [ncbi taxid: 313913]
  44. Baptisia lanceolata [ncbi taxid: 1969221]
  45. Baptisia nuttalliana [ncbi taxid: 3120271]
  46. Baptisia perfoliata [ncbi taxid: 1871516]
  47. Baptisia simplicifolia [ncbi taxid: 1969224]
  48. Baptisia tinctoria [ncbi taxid: 49797]
  49. Berberis crataegina [ncbi taxid: 2602221]
  50. Berberis japonica [ncbi taxid: 116719]
  51. Bersama swinnyi [ncbi taxid: 377272]
  52. Blainvillea latifolia [ncbi taxid: ]
  53. Boletinus paluster [ncbi taxid: ]
  54. Bothriocline laxa [ncbi taxid: 434626]
  55. Brachylaena discolor var. rotundata [ncbi taxid: 1237404]
  56. Byrsonima crassifolia [ncbi taxid: 4270]
  57. Byssovorax cruenta [ncbi taxid: 293647]
  58. Calceolaria thyrsiflora [ncbi taxid: 240994]
  59. Calodendrum capense [ncbi taxid: 68533]
  60. Calophyllum thwaitesii [ncbi taxid: ]
  61. Cardiopetalum calophyllum [ncbi taxid: 2025453]
  62. Ceanothus intergerrimus [ncbi taxid: ]
  63. Celtis spp. [ncbi taxid: ]
  64. Centaurium pulchellum [ncbi taxid: 172069]
  65. Ceroplastes pseudoceriferus [ncbi taxid: 1182651]
  66. Chamaecyparis pisifera [ncbi taxid: 99808]
  67. Cheilanthes marantae [ncbi taxid: ]
  68. Chondrosia reniformis [ncbi taxid: 68574]
  69. Choriaster granulatus [ncbi taxid: 2999172]
  70. Cirsium dipsacolepis [ncbi taxid: 3366973]
  71. Citrus trifolia [ncbi taxid: ]
  72. Clusia nemorosa [ncbi taxid: 180924]
  73. Cocculus diversifolius [ncbi taxid: ]
  74. Conyza bonariensis [ncbi taxid: 91242]
  75. Coptis trifolia subsp. groenlandica [ncbi taxid: 1844482]
  76. Cortinarius vinosipes [ncbi taxid: 2876164]
  77. Crassocephalum crepidioides [ncbi taxid: 189211]
  78. Crataegus pontica [ncbi taxid: ]
  79. Crinum kirkii [ncbi taxid: 209098]
  80. Croton caudatus [ncbi taxid: 323037]
  81. Croton rhamnifolius [ncbi taxid: ]
  82. Cryptocarya pleurosperma [ncbi taxid: 1312791]
  83. Cytisus scoparius [ncbi taxid: 3835]
  84. Dermocybe cardinalis [ncbi taxid: ]
  85. Diaporthe amygdali [ncbi taxid: 1214568]
  86. Dictamnus gymnostylis [ncbi taxid: ]
  87. Dioscorea gracillima [ncbi taxid: 64699]
  88. Diplolophium buchananii [ncbi taxid: ]
  89. Echinocystis lobata [ncbi taxid: 252533]
  90. Echium rubrum [ncbi taxid: 3046405]
  91. Eichhornia crassipes [ncbi taxid: ]
  92. Elaeocarpus fuscoides [ncbi taxid: ]
  93. Elysia grandifolia [ncbi taxid: ]
  94. Engelhardia spicata [ncbi taxid: 139933]
  95. Entada africana [ncbi taxid: 2005481]
  96. Entada polystachya [ncbi taxid: 489317]
  97. Epimedium wushanense [ncbi taxid: 253611]
  98. Eria subsessilis [ncbi taxid: ]
  99. Erycibe obtusifolia [ncbi taxid: 1603722]
  100. Erycibe schmidtii [ncbi taxid: 2315750]
  101. Euonymus phellomanus [ncbi taxid: 1089404]
  102. Euphorbia resinifera [ncbi taxid: 457265]
  103. Euplotes rariseta [ncbi taxid: 98374]
  104. Eurycoma longifolia [ncbi taxid: 458531]
  105. Euryops pedunculatus [ncbi taxid: ]
  106. Fasciospongia rimosa [ncbi taxid: ]
  107. Felicia amelloides [ncbi taxid: 696374]
  108. Ficus ruficaulis [ncbi taxid: 479338]
  109. Fucus spiralis [ncbi taxid: 87149]
  110. Fuligo candida [ncbi taxid: 289946]
  111. Fumaria indica [ncbi taxid: 1464615]
  112. Garcinia purpurea [ncbi taxid: ]
  113. Geigeria schinzii [ncbi taxid: 1548584]
  114. Gentianella nitida [ncbi taxid: 2576744]
  115. Geranium sanguineum [ncbi taxid: 70270]
  116. Gleichenia japonica [ncbi taxid: 3274]
  117. Glossogyne tenuifolia [ncbi taxid: 260272]
  118. Gnathotrichus sulcatus [ncbi taxid: 929056]
  119. Goniothalamus undulatus [ncbi taxid: 497617]
  120. Haemanthus toxicarius [ncbi taxid: ]
  121. Hedera spp. [ncbi taxid: ]
  122. Helenium quadridentatum [ncbi taxid: 1448041]
  123. Helianthus annuus [ncbi taxid: 4232]
  124. Helichrysum angustifolium [ncbi taxid: ]
  125. Helichrysum sutherlandii [ncbi taxid: 1442697]
  126. Heliotropium europaeum [ncbi taxid: 168345]
  127. Hendersonula toruloidea [ncbi taxid: ]
  128. Heterosigma akashiwo [ncbi taxid: 2829]
  129. Hymenocallis littoralis [ncbi taxid: 59040]
  130. Hymenoxys microcephala [ncbi taxid: 128724]
  131. Hypericum triquetrifolium [ncbi taxid: 282558]
  132. Iberis sempervirens [ncbi taxid: 359854]
  133. Isodon gesneroides [ncbi taxid: 662912]
  134. Isodon japonicus [ncbi taxid: 425908]
  135. Isodon nervosus [ncbi taxid: 662921]
  136. Isodon xerophilus [ncbi taxid: 662931]
  137. Jacobaea adonidifolia [ncbi taxid: 189226]
  138. Juniperus rigida [ncbi taxid: 99809]
  139. Knightia deplanchei [ncbi taxid: ]
  140. Lecanora hybocarpa [ncbi taxid: 394998]
  141. Lecanora melanophthalma [ncbi taxid: ]
  142. Lechevalieria aerocolonigenes [ncbi taxid: ]
  143. Leontice kiangnanensis [ncbi taxid: ]
  144. Lepraria xanthina [ncbi taxid: ]
  145. Limnocitrus littoralis [ncbi taxid: ]
  146. Lonchocarpus longistylus [ncbi taxid: 1582191]
  147. Lonchocarpus oaxacensis [ncbi taxid: 1582200]
  148. Lonicera fulvotomentosa [ncbi taxid: 643838]
  149. Lophiostoma vaginatispora [ncbi taxid: 1503222]
  150. Lophocereus marginatus [ncbi taxid: 154435]
  151. Lycium barbarum [ncbi taxid: 112863]
  152. Lycium chinense [ncbi taxid: 112883]
  153. Macaranga tanarius [ncbi taxid: 109849]
  154. Malva sylvestris [ncbi taxid: 145754]
  155. Mandragora autumnalis [ncbi taxid: 389206]
  156. Manihot esculenta [ncbi taxid: 3983]
  157. Meconopsis horridula [ncbi taxid: 248837]
  158. Medium grandiflorum [ncbi taxid: ]
  159. Melaleuca decora [ncbi taxid: ]
  160. Mesembryanthemum anatomicum [ncbi taxid: ]
  161. Miscanthus sacchariflorus [ncbi taxid: 183675]
  162. Monanchora unguiculata [ncbi taxid: 1346142]
  163. Monomeria barbata [ncbi taxid: 1898896]
  164. Morus alba [ncbi taxid: 3498]
  165. Morus alba L. [ncbi taxid: ]
  166. Murraya paniculata [ncbi taxid: 43711]
  167. Myrica multiflora [ncbi taxid: ]
  168. Nama johnstonii [ncbi taxid: ]
  169. Narcissus pseudonarcissus subsp. leonensis [ncbi taxid: ]
  170. Nemuaron humboldtii [ncbi taxid: ]
  171. Nepeta leucophylla [ncbi taxid: ]
  172. Nephila clavata [ncbi taxid: ]
  173. Nerium odorum [ncbi taxid: ]
  174. Nerium oleander [ncbi taxid: 63479]
  175. Nicotiana tabacum [ncbi taxid: 4097]
  176. Ophiarthrum elegans [ncbi taxid: ]
  177. Ophryosporus charua [ncbi taxid: ]
  178. Ormosia excelsa [ncbi taxid: 1231561]
  179. Oxera splendida [ncbi taxid: 54231]
  180. Pachycereus pringlei [ncbi taxid: 154437]
  181. Papaver radicatum [ncbi taxid: 357475]
  182. Paramignya griffithii [ncbi taxid: ]
  183. Parerythropodium fulvum [ncbi taxid: ]
  184. Parmelia pokornyi [ncbi taxid: ]
  185. Penicillium alutaceum [ncbi taxid: 70088]
  186. Penicillium crustaceum [ncbi taxid: ]
  187. Pericopsis schliebenii [ncbi taxid: ]
  188. Phellinus igniarius [ncbi taxid: 40472]
  189. Philotheca pachyphylla [ncbi taxid: 2999144]
  190. Phlomoides medicinalis [ncbi taxid: 1138144]
  191. Physochlaina physaloides [ncbi taxid: 337186]
  192. Pinus glauca [ncbi taxid: ]
  193. Plantago lanceolata [ncbi taxid: 39414]
  194. Plectranthus nummularius [ncbi taxid: ]
  195. Plectranthus saccatus [ncbi taxid: ]
  196. Podocarpus montanus [ncbi taxid: ]
  197. Pogonopus speciosus [ncbi taxid: 43555]
  198. Polysiphonia fastigiata [ncbi taxid: ]
  199. Polytolypa hystricis [ncbi taxid: 221428]
  200. Prosopis kuntzei [ncbi taxid: ]
  201. Pseudophryne coriacea [ncbi taxid: 356242]
  202. Pseuduvaria indochinensis [ncbi taxid: 1679246]
  203. Pteris inaequalis [ncbi taxid: 2815894]
  204. Pteris setuloso-costulata [ncbi taxid: ]
  205. Pteris spinulosa [ncbi taxid: ]
  206. Ptilidium ciliare [ncbi taxid: 139839]
  207. Pulicaria uliginosa [ncbi taxid: ]
  208. Pyrenula japonica [ncbi taxid: ]
  209. Quercus ithaburensis subsp. macrolepis [ncbi taxid: 58332]
  210. Rhodoglossum japonicum [ncbi taxid: ]
  211. Rhodopila globiformis [ncbi taxid: 1071]
  212. Rhus lanceolata [ncbi taxid: 289755]
  213. Rhynchosporium orthosporum [ncbi taxid: ]
  214. Roccellaria mollis [ncbi taxid: 415645]
  215. Roemeria carica [ncbi taxid: ]
  216. Russula sardonia [ncbi taxid: 152970]
  217. Ruta bracteosa [ncbi taxid: ]
  218. Santolina oblongifolia [ncbi taxid: 634960]
  219. Saussurea cordifolia [ncbi taxid: 3030892]
  220. Schefflera divaricata [ncbi taxid: ]
  221. Schisandra arisanensis [ncbi taxid: 453241]
  222. Schumanniophyton magnificum [ncbi taxid: 114490]
  223. Sclerodoris tanya [ncbi taxid: ]
  224. Scopolia carniolica [ncbi taxid: 258457]
  225. Scopolia japonica [ncbi taxid: 221162]
  226. Scopolia parviflora [ncbi taxid: 258455]
  227. Scutellaria seleriana [ncbi taxid: 2798891]
  228. Senecio oxyodontus [ncbi taxid: 2962182]
  229. Senecio polyodon [ncbi taxid: 1892290]
  230. Senna sophera [ncbi taxid: 948718]
  231. Solanum racemigerum [ncbi taxid: ]
  232. Sophora davidii [ncbi taxid: 49839]
  233. Sophora japonica [ncbi taxid: ]
  234. Stenocereus thurberi [ncbi taxid: 171973]
  235. Stevia purpurea [ncbi taxid: ]
  236. Streptomyces alboflavus [ncbi taxid: 67267]
  237. Streptomyces eurythermus [ncbi taxid: 42237]
  238. Streptomyces kanamyceticus [ncbi taxid: 1967]
  239. Strychnos angustiflora [ncbi taxid: 1040857]
  240. Strychnos parvifolia [ncbi taxid: 1040913]
  241. Swartzia madagascariensis [ncbi taxid: ]
  242. Swertia spp. [ncbi taxid: ]
  243. Talaromyces convolutus [ncbi taxid: 1131474]
  244. Tecoma heptaphylla [ncbi taxid: ]
  245. Tephrosia barbigera [ncbi taxid: ]
  246. Teucrium pestalozzae [ncbi taxid: 1854044]
  247. Thamnophis sirtalis [ncbi taxid: 35019]
  248. Thiocystis gelatinosa [ncbi taxid: 46450]
  249. Tithonia rotundifolia [ncbi taxid: 105388]
  250. Toona febrifuga [ncbi taxid: ]
  251. Tragopogon porrifolius [ncbi taxid: 13731]
  252. Tricholoma batschii [ncbi taxid: 76321]
  253. Trifolium apertum [ncbi taxid: 361886]
  254. Tripodanthus acutifolius [ncbi taxid: 50169]
  255. Trivalvaria macrophylla [ncbi taxid: 235846]
  256. Ulmus thomasii [ncbi taxid: 180953]
  257. Urechis caupo [ncbi taxid: 6431]
  258. Veronica pectinata [ncbi taxid: 207271]
  259. Verpa digitaliformis [ncbi taxid: 159284]
  260. Viburnum awabuki [ncbi taxid: 453244]
  261. Viguiera annua [ncbi taxid: ]
  262. Virola sebifera [ncbi taxid: 224866]
  263. Vitex limonifolia [ncbi taxid: 413483]
  264. Vitex negundo [ncbi taxid: 361442]
  265. Vitex pinnata [ncbi taxid: 548852]
  266. Wolfiporia cocos [ncbi taxid: 81056]
  267. Xanthoparmelia pokornyi [ncbi taxid: 164177]
  268. Xerula melanotricha [ncbi taxid: 302556]
  269. Xestospongia muta [ncbi taxid: 178552]
  270. [polyangium] brachysporum [ncbi taxid: ]

Pathway Synthetic

pathway id name
BioCyc:META_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:SOY_PWY4FS-10 scopolin biosynthesis
PlantCyc:ALYRATA_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:SWITCHGRASS_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:ASPARAGUS_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:BANANA_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:BOLERACEA_CAPITATA_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:BRAPA_FPSC_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:BSTRICTA_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:CARIETINUM_ICC4958_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:POPLAR_PWY4FS-10 scopolin biosynthesis
PlantCyc:POTATO_PWY4FS-10 scopolin biosynthesis
PlantCyc:REDSAGE_PWY4FS-10 scopolin biosynthesis
PlantCyc:SACREDLOTUS_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:SACREDLOTUS_PWY4FS-10 scopolin biosynthesis
PlantCyc:SOLERACEA_PWY4FS-10 scopolin biosynthesis
PlantCyc:COCOA_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:CORN_PWY4FS-10 scopolin biosynthesis
PlantCyc:CROSEUS_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:VALLEYOAK_PWY4FS-10 scopolin biosynthesis
View All Pathways