Retinol-(cellular-retinol-binding-protein) (BioCAD00000017232)
blood feces saliva adipose tissue epidermis fibroblasts intestine kidney liver neuron placenta spleen testis
Metabolite Card
Formula: C20H30O (286.2297)
SMILES: C\C(=C/CO)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C
Synonyms [en]
trans-retinol; Retinol; vitamin A; vitamin A1; Aquasol A; (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol
Last reviewed on 2024-06-28.
Cite this Page
Retinol-(cellular-retinol-binding-protein). 数据之源,洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000017232). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Vitamin A (retinol) is a yellow fat-soluble, antioxidant vitamin important in vision and bone growth. It belongs to the family of chemical compounds known as retinoids. Retinol is ingested in a precursor form; animal sources (milk and eggs) contain retinyl esters, whereas plants (carrots, spinach) contain pro-vitamin A carotenoids. Hydrolysis of retinyl esters results in retinol while pro-vitamin A carotenoids can be cleaved to produce retinal. Retinal, also known as retinaldehyde, can be reversibly reduced to produce retinol or it can be irreversibly oxidized to produce retinoic acid. Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.
DBLinks
- CAS Registry Number: 68-26-8
- PubChem CID: 445354
- ChEBI: 17336
- HMDB: HMDB0000305
- LipidMaps: LMPR01090001
- KEGG: C17276
- BioCyc: CPD-13524
- NCBI MeSH:
- Wikipedia: Vitamin_A
Other DBLinks
- CAS Registry Number: 11103-57-4
- CAS Registry Number: 68-26-8
- PubChem: 445354
- ChEBI: ChEBI:17336
- HMDB: HMDB0000305
- LipidMaps: LMPR01090001
- KEGG: C17276
- BioCyc: CPD-13524
- Wikipedia: Retinol
- Wikipedia: Vitamin_A
- DrugBank: DB00162
Class / Ontology
- WishartLab ClassyFire: [Retinoids] Retinoids
- ChEBI: [CHEBI:17336] all-trans-retinol
| ID | EC Number | Name |
|---|---|---|
| KEGG:R04514 | 2.3.1.135 | phosphatidylcholine:retinol-(cellular-retinol-binding-protein) O-acyltransferase |
| BioCyc:RXN-18778 | 1.14.19.53 | CPD-13524 + OXYGEN-MOLECULE + 2 Reduced-adrenal-ferredoxins + 2 PROTON --> CPD-20073 + 2 WATER + 2 Oxidized-adrenal-ferredoxins |
| BioCyc:3.1.1.64-RXN | 3.1.1.1 | all-trans-retinyl-palmitate hydrolase |
| BioCyc:RXN-10841 | 1.1.1.300 | CPD-13524 + NADP<=>RETINAL + NADPH + PROTON |
| BioCyc:RXN-12548 | CPD-13524 + Cellular-Retinol-Binding-Proteins --> CRPB-all-trans-Retinol | |
| BioCyc:RXN-12549 | CPD-13524 + Retinol-Binding-Proteins<=>RPB-Retinol | |
| BioCyc:RXN-12575 | 3.1.1.1 | all-trans retinyl-ester hydrolase |
| BioCyc:RETINOL-DEHYDROGENASE-RXN | 1.1.1.105 | all-trans-retinol dehydrogenase (NAD) |
| BioCyc:RXN66-660 | 1.14.14.- | CPD-13524 + OXYGEN-MOLECULE + Red-NADPH-Hemoprotein-Reductases --> RETINAL + 2 WATER + Ox-NADPH-Hemoprotein-Reductases |
| BioCyc:RXN-12547 | 2.3.1.76 | PALMITYL-COA + CPD-13524 --> CHOCOLA_A + CO-A |
| BioCyc:RETINOL-O-FATTY-ACYLTRANSFERASE-RXN | 2.3.1.76 | CPD-13524 + ACYL-COA<=>All-trans-Retinyl-Esters + CO-A |
| BioCyc:1.3.99.23-RXN | 1.3.99.23 | CPD-13524 + Donor-H2 --> CPD-7247 + Acceptor |
| BioCyc:RXN-12579 | 3.1.1.3 | Dietary-retinyl-esters + WATER --> CPD-13524 + Fatty-Acids + PROTON |