Metabolite Card
Formula: C4H9Cl2N (141.0112)
SMILES: ClCCNCCCl
Synonyms [en]
nornitrogen mustard; Nor-nitrogen mustard; 2,2'-Dichlorodiethylamine; NH-Lost; Bis(chloroethyl)amine; bis(2-chloroethyl)amine
Last reviewed on 2024-06-28.
Cite this Page
Nornitrogen mustard. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000015334). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Nornitrogen mustard is a metabolite of cyclophosphamide. Cyclophosphamide (trade names Endoxan, Cytoxan, Neosar, Procytox, Revimmune), also known as cytophosphane, is a nitrogen mustard alkylating agent, from the oxazophorines group. An alkylating agent adds an alkyl group (CnH2n+1) to DNA. It attaches the alkyl group to the guanine base of DNA, at the number 7 nitrogen atom of the imidazole ring. It is used to treat various types of cancer and some autoimmune disorders. (Wikipedia)
DBLinks
- CAS Registry Number: 334-22-5
- PubChem CID: 9533
- ChEBI: 37599
- HMDB: HMDB0060688
- LipidMaps:
- KEGG: C16552
- BioCyc:
- NCBI MeSH: nornitrogen mustard
- Wikipedia:
Other DBLinks
- CAS Registry Number: 334-22-5
- PubChem: 9533
- ChEBI: ChEBI:37599
- HMDB: HMDB0060688
- KEGG: C16552
- NCBI MeSH: nornitrogen mustard
- RefMet: RM0200006
- Metlin: METLIN_635
Class / Ontology
- WishartLab ClassyFire: [Nitrogen mustard compounds] Nitrogen mustard compounds
- RefMet: [Nitrogen mustard compounds] Nitrogen mustard compounds
- ChEBI: [CHEBI:37599] bis(2-chloroethyl)amine
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| PathBank:SMP0000447 | Cyclophosphamide Action Pathway |
| PathBank:SMP0000604 | Cyclophosphamide Metabolism Pathway |