N-Ethylglycine (BioCAD00000014664)
Metabolite Card
Formula: C4H9NO2 (103.0633)
SMILES: CCNCC(O)=O
Synonyms [en]
N-Ethylglycine; EtGly; 2-(ethylamino)acetic acid; N-ethyl glycine; YPIGGYHFMKJNKV-UHFFFAOYSA-; 2-Ethylaminoacetic acid
Last reviewed on 2024-06-28.
Cite this Page
N-Ethylglycine. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000014664). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
N-Ethylglycine, also known as EG, belongs to the family of compounds known as alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). N-ethylglyicne is a known metabolite of the anesthesia drug lidocaine (PMID: 25932687). N-ethylglyicne is also an endogenously produced metabolite and appears in normal subjects’ urine in small amounts, but its presence is significantly higher in patients with metastatic bone disease (PMID: 16962088). Research has shown that it is lidocaine’s metabolites, n-ethylglycine and monoethylglycinexylidide inhibit GlyT1-mediated uptake of glycine. N-ethylglycine acts as a substrate for the glycine transporter GlyT1 (PMID: 22133759, 25932687).
DBLinks
- CAS Registry Number: 627-01-0
- PubChem CID: 6992079
- ChEBI: 15620
- HMDB: HMDB0041945
- LipidMaps:
- KEGG: C11735
- BioCyc:
- NCBI MeSH: N-ethylglycine
- Wikipedia: Alpha-Aminobutyric acid
Other DBLinks
- CAS Registry Number: 627-01-0
- PubChem: 316542
- PubChem: 6992079
- ChEBI: ChEBI:15620
- HMDB: HMDB0041945
- KEGG: C11735
- NCBI MeSH: N-ethylglycine
- Wikipedia: Alpha-Aminobutyric acid
- RefMet: RM0052733
- MoNA: FiehnLib000203
- MoNA: FiehnLib000204
- MoNA: HMDB0041945_c_ms_102292
- MoNA: HMDB0041945_c_ms_102293
- Metlin: METLIN_69186
- Coconut NaturalProduct: CNP0076362.0
Class / Ontology
- WishartLab ClassyFire: [Amino acids, peptides, and analogues] Amino acids, peptides, and analogues
- RefMet: [Amino acids] Amino acids
- ChEBI: [CHEBI:15620] N-ethylglycine
- Coconut NaturalProduct: [Aminoacids] Aminoacids
| ID | EC Number | Name |
|---|---|---|
| KEGG:R05863 | 1.4.3.19 | N-ethylglycine:oxygen oxidoreductase (deaminating) |
| KEGG:R08295 | 3.1.1.1 | monoethylglycinexylidide amidohydrolase |