N-Acetyl-L-glutamate 5-semialdehyde (BioCAD00000014539)
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Metabolite Card
Formula: C7H11NO4 (173.0688)
SMILES: CC(=O)N[C@@H](CCC=O)C(O)=O
Synonyms [en]
N-Acetyl-L-glutamate 5-semialdehyde; (2S)-2-acetamido-5-oxopentanoic acid; N-Acetyl-5-oxo-L-norvaline; 2-Acetamido-5-oxopentanoic acid; 2-Acetamido-5-oxovaleric acid; N-acetyl-L-glutamic acid gamma-semialdehyde
Last reviewed on 2024-06-28.
Cite this Page
N-Acetyl-L-glutamate 5-semialdehyde. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000014539). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
N-Acetyl-L-glutamate 5-semialdehyde is an intermediate in Urea cycle and metabolism of amino groups. N-Acetyl-L-glutamate 5-semialdehyde is the. second to last step in the synthesis of L-Ornithine and is converted. from N-Acetyl-L-glutamate 5-phosphate via the enzyme N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38). It is then converted to N-Acetylornithine via the enzyme acetylornithine aminotransferase (EC 2.6.1.11).
DBLinks
- CAS Registry Number: 13074-21-0
- PubChem CID: 192878
- ChEBI: 16319
- HMDB: HMDB0006488
- LipidMaps:
- KEGG: C01250
- BioCyc:
- NCBI MeSH: N-acetyl-L-glutamic acid gamma-semialdehyde
- Wikipedia:
Other DBLinks
- CAS Registry Number: 13074-21-0
- PubChem: 192878
- ChEBI: ChEBI:16319
- HMDB: HMDB0006488
- KEGG: C01250
- NCBI MeSH: N-acetyl-L-glutamic acid gamma-semialdehyde
- RefMet: RM0040848
- Metlin: METLIN_3298
- Coconut NaturalProduct: CNP0055559.1
Class / Ontology
- WishartLab ClassyFire: [Amino acids, peptides, and analogues] Amino acids, peptides, and analogues
- RefMet: [Amino acids] Amino acids
- ChEBI: [CHEBI:16319] 2-acetamido-5-oxopentanoic acid
- Coconut NaturalProduct: [Dipeptides] Dipeptides
| ID | EC Number | Name |
|---|---|---|
| KEGG:R02283 | 2.6.1.11 | N2-acetyl-L-ornithine:2-oxoglutarate aminotransferase |
| KEGG:R03443 | 1.2.1.38 | N-acetyl-L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphrylating) |
| KEGG:R12085 | 2.3.1.271 | acetyl-CoA:L-glutamate-5-semialdehyde N-acetyltransferase |