Marinobufagenin (BioCAD00000013735)

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Metabolite Card

Formula: C24H32O5 (400.225)
SMILES: CC12CCC(CC1(CCC3C2CCC4(C35C(O5)CC4C6=COC(=O)C=C6)C)O)O

Synonyms [en]

Marinobufagenin; Marinobufagin; 3KBT25GV2B; MARCINOBUFAGIN; Marinobufogenin; UNII-3KBT25GV2B

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Marinobufagenin. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000013735). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Marinobufagenin is a cardiotonic steroid secreted by the toad Bufo rubescens and other related species such as Bufo marinus. An endogenous Na/K-ATPase inhibitor, it is a vasoconstrictor with effects similar to digitalis. It has a role as an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor and an epitope. It is a steroid hormone and an epoxy steroid. It is functionally related to a (5beta)-bufadienolide. Marinobufagenin is a natural product found in Phrynoidis asper, Bufo bufo, and other organisms with data available. Marinobufagin is a cardiotoxic bufanolide steroid secreted by certain toads (Bufo rubescens, Bufo marinus). It is a vasoconstrictor. (L1085)

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 470-42-8
  • PubChem: 11969465
  • ChEBI: ChEBI:146151
  • KEGG: C20036
  • NCBI MeSH: marinobufagenin
  • Wikipedia: Marinobufagenin
  • Metlin: METLIN_73521
  • Coconut NaturalProduct: CNP0128303.1
  • Coconut NaturalProduct: CNP0202730.1
  • Coconut NaturalProduct: CNP0290788.1
  • Coconut NaturalProduct: CNP0424721.1
  • Coconut NaturalProduct: CNP0424721.2

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

  1. Ambrosia artemisioides [ncbi taxid: 2067507]
  2. Cephalotaxus fortunei [ncbi taxid: 66169]
  3. Selenarctos thibetanus [ncbi taxid: ]
  4. Alicyclobacillus cycloheptanicus [ncbi taxid: 1457]
  5. Artemisia oranensis [ncbi taxid: 1903224]
  6. Aruncus dioicus [ncbi taxid: 32220]
  7. Astragalus globiceps [ncbi taxid: 3084141]
  8. Bufo bufo [ncbi taxid: 8384]
  9. Buxus sempervirens [ncbi taxid: 4002]
  10. Cabucala madagascariensis [ncbi taxid: ]
  11. Centaurea amara [ncbi taxid: ]
  12. Chamaemelum nobile [ncbi taxid: 99037]
  13. Cortinarius rubellus [ncbi taxid: 86073]
  14. Cupressus macrocarpa [ncbi taxid: ]
  15. Doronicum hungaricum [ncbi taxid: 118765]
  16. Dysoxylum lenticellatum [ncbi taxid: ]
  17. Gavia immer [ncbi taxid: 37039]
  18. Halimeda macroloba [ncbi taxid: 170422]
  19. Hammada elegans [ncbi taxid: ]
  20. Haplopappus venetus [ncbi taxid: ]
  21. Hedyotis verticillata [ncbi taxid: ]
  22. Ilex paraguariensis [ncbi taxid: 185542]
  23. Kochia trichophylla [ncbi taxid: ]
  24. Lecanora conizaeoides [ncbi taxid: 128387]
  25. Lytanthus salicinus [ncbi taxid: ]
  26. Microlepia marginata [ncbi taxid: 749682]
  27. Phebalium ozothamnoides [ncbi taxid: ]
  28. Piper futokadsura [ncbi taxid: ]
  29. Pleurotus citrinopileatus [ncbi taxid: 98342]
  30. Potentilla multifida [ncbi taxid: 210859]
  31. Psorothamnus spinosus [ncbi taxid: 248539]
  32. Rhaponticum carthamoides [ncbi taxid: ]
  33. Saururus cernuus [ncbi taxid: 13260]
  34. Streptomyces plumbeus [ncbi taxid: 285475]
  35. Strychnos fendleri [ncbi taxid: 1040884]
  36. Vicia villosa [ncbi taxid: 3911]
  37. Vitex megapotamica [ncbi taxid: 1365883]
  38. Ambrosia artemisioides [ncbi taxid: 2067507]

Pathway Synthetic

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