Hypotaurine (BioCAD00000012305)

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Metabolite Card

Formula: C2H7NO2S (109.0197)
SMILES: NCCS(O)=O

Synonyms [en]

Hypotaurine; 2-Aminoethanesulfinic acid; 2-amino-Ethanesulfinic acid; Cystaminesulfinate; 2-Aminoethylsulfinic acid; 2-aminoethane-1-sulfinic acid

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Hypotaurine. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000012305). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Hypotaurine belongs to the class of organic compounds known as sulfinic acids. Sulfinic acids are compounds containing a sulfinic acid functional group, with the general structure RS(=O)OH (R = organyl, not H). Hypotaurine exists in all living species, ranging from bacteria to humans. Within humans, hypotaurine participates in a number of enzymatic reactions. In particular, hypotaurine can be biosynthesized from cysteamine; which is catalyzed by the enzyme 2-aminoethanethiol dioxygenase. In addition, hypotaurine can be biosynthesized from 3-sulfinoalanine through its interaction with the enzyme cysteine sulfinic acid decarboxylase. In humans, hypotaurine is involved in taurine and hypotaurine metabolism.

Cytoplasm
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 300-84-5
  • PubChem: 107812
  • PubChem: 3802
  • ChEBI: ChEBI:16668
  • HMDB: HMDB0000965
  • KEGG: C00519
  • BioCyc: HYPOTAURINE
  • NCBI MeSH: hypotaurine
  • Wikipedia: Hypotaurine
  • RefMet: RM0136027
  • MoNA: BAF_UVA_POS000060
  • MoNA: BAF_UVA_POS000921
  • MoNA: BAF_UVA_POS000922
  • MoNA: CCMSLIB00000577883
  • MoNA: CCMSLIB00000578094
  • MoNA: CCMSLIB00005463934
  • MoNA: CCMSLIB00005720596
  • MoNA: CCMSLIB00005720613
  • MoNA: EMBL-MCF_spec91851
  • MoNA: EMBL_MCF_2_0_HRMS_Library000050
  • MoNA: EMBL_MCF_2_0_HRMS_Library000051
  • MoNA: EMBL_MCF_2_0_HRMS_Library000291
  • MoNA: GLS00019
  • MoNA: HMDB0000965_c_ms_1280
  • MoNA: HMDB0000965_ms_ms_1369
  • MoNA: HMDB0000965_ms_ms_1370
  • MoNA: HMDB0000965_ms_ms_1371
  • MoNA: KNA00013
  • MoNA: KNA00014
  • MoNA: KNA00016
  • MoNA: KNA00404
  • MoNA: KNA00405
  • MoNA: KNA00406
  • MoNA: KNA00407
  • MoNA: KO000993
  • MoNA: KO000994
  • MoNA: KO000995
  • MoNA: KO000996
  • MoNA: KO000997
  • MoNA: KO003083
  • MoNA: KO003084
  • MoNA: KO003085
  • MoNA: KO003086
  • MoNA: KO003087
  • MoNA: KZ000034
  • MoNA: MoNA002047
  • MoNA: MoNA002050
  • MoNA: MoNA002051
  • MoNA: MoNA011111
  • MoNA: MoNA011112
  • MoNA: MoNA011113
  • MoNA: MoNA011114
  • MoNA: MoNA024331
  • MoNA: MoNA033601
  • MoNA: MoNA033602
  • MoNA: MoNA033603
  • MoNA: MoNA037090
  • MoNA: MoNA038507
  • MoNA: OUF00272
  • MoNA: PR010027
  • MoNA: PR100146
  • MoNA: PR100568
  • MoNA: PS025101
  • MoNA: PS025102
  • MoNA: PS025103
  • MoNA: PT102510
  • MoNA: PT202510
  • Metlin: METLIN_281

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R02466 4.1.1.15 3-sulfino-L-alanine carboxy-lyase
KEGG:R02467 1.13.11.19 cysteamine:oxygen oxidoreductase
KEGG:R12959 1.8.1.- C00519 + C00005 + C00080 + C00007<=>C00245 + C00006 + C00001
BioCyc:TRANS-RXN0-509 HYPOTAURINE --> HYPOTAURINE
BioCyc:CYSTEAMINE-DIOXYGENASE-RXN 1.13.11.19 OXYGEN-MOLECULE + CPD-239 --> PROTON + HYPOTAURINE
BioCyc:HYPOTAURINE-DEHYDROGENASE-RXN 1.8.1.3 HYPOTAURINE + WATER + NAD --> TAURINE + NADH + PROTON
BioCyc:SULFINOALANINE-DECARBOXYLASE-RXN 4.1.1.29 PROTON + 3-SULFINOALANINE --> HYPOTAURINE + CARBON-DIOXIDE
BioCyc:RXN-14907 2.6.1.77 PYRUVATE + HYPOTAURINE<=>L-ALPHA-ALANINE + CPD-15830
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
WikiPathways:WP2525 Trans-sulfuration, one-carbon metabolism and related pathways
WikiPathways:WP3604 Biochemical pathways: part I
WikiPathways:WP1770 One-carbon metabolism and related pathways
WikiPathways:WP4292 Methionine metabolism leading to sulfur amino acids and related disorders
WikiPathways:WP3125 One-carbon donor
WikiPathways:WP3940 One-carbon metabolism and related pathways
PathBank:SMP0087309 Taurine and Hypotaurine Metabolism
PathBank:SMP0002379 Taurine and Hypotaurine Biosynthesis
PathBank:SMP0000021 Taurine and Hypotaurine Metabolism
PathBank:SMP0087214 Taurine and Hypotaurine Metabolism
PathBank:SMP0063675 Taurine and Hypotaurine Metabolism
View All Pathways