Esculin (BioCAD00000010699)

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Metabolite Card

Formula: C15H16O9 (340.0794)
SMILES: OC[C@H]1O[C@@H](OC2=C(O)C=C3OC(=O)C=CC3=C2)[C@H](O)[C@@H](O)[C@@H]1O

Synonyms [en]

Esculin; aesculin; Esculoside; Esculetin 6-beta-D-glucoside; Esculetin 6-O-glucoside; 6-(beta-D-Glucopyranosyloxy)-7-hydroxy-cumarin

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Esculin. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000010699). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Aesculin is found in barley. Vitamin C2 is generally considered a bioflavanoid, related to vitamin P Aesculin is a glucoside that naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and in daphnin (the dark green resin of Daphne mezereum)

Cytoplasm Extracellular
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 531-75-9
  • CAS Registry Number: 66778-17-4
  • PubChem: 5281417
  • PubChem: 5351506
  • PubChem: 6931338
  • ChEBI: ChEBI:4853
  • HMDB: HMDB0030820
  • KEGG: C09264
  • BioCyc: 14461
  • BioCyc: CPD-14461
  • NCBI MeSH: Esculin
  • Wikipedia: Aesculin
  • DrugBank: DB13155
  • RefMet: RM0136970
  • MoNA: BML00468
  • MoNA: BML00486
  • MoNA: BML00495
  • MoNA: BML00503
  • MoNA: BML00511
  • MoNA: BML81215
  • MoNA: BML81216
  • MoNA: BML81217
  • MoNA: BML81218
  • MoNA: CB000248
  • MoNA: MoNA033009
  • MoNA: MoNA033013
  • MoNA: MoNA033014
  • MoNA: MoNA035197
  • MoNA: MoNA035198
  • MoNA: MoNA035199
  • MoNA: MoNA037478
  • MoNA: MoNA038231
  • MoNA: NGA01769
  • MoNA: NGA01770
  • MoNA: NGA01771
  • MoNA: NGA01772
  • MoNA: PM000313
  • MoNA: PR100475
  • MoNA: PR100940
  • MoNA: PS125101
  • MoNA: PS125102
  • MoNA: PS125103
  • MoNA: PS125104
  • MoNA: PS125105
  • MoNA: PS125106
  • MoNA: PS125107
  • MoNA: PS125108
  • MoNA: PS125109
  • MoNA: PS125110
  • MoNA: PS125111
  • MoNA: PS125112
  • MoNA: PT112510
  • MoNA: PT212510
  • MoNA: VF-NPL-LTQ006675
  • MoNA: VF-NPL-LTQ006676
  • MoNA: VF-NPL-QTOF006527
  • MoNA: VF-NPL-QTOF006528
  • MoNA: VF-NPL-QTOF006529
  • MoNA: VF-NPL-QTOF006530
  • MoNA: VF-NPL-QTOF006531
  • MoNA: VF-NPL-QTOF006532
  • Metlin: METLIN_43929
  • Coconut NaturalProduct: CNP0168241.2
  • Coconut NaturalProduct: CNP0214412.1
  • Coconut NaturalProduct: CNP0214412.3
  • Coconut NaturalProduct: CNP0214412.4
  • Coconut NaturalProduct: CNP0214412.5
  • Coconut NaturalProduct: CNP0214412.7

Class / Ontology

Metabolic Network
ID EC Number Name
BioCyc:RXN-13470 2.4.1.- cichoriin transglucosylase (6-O-glucosyltransferase activity)
BioCyc:RXN-14182 2.4.1.- CPD-12575 + CPD-8097 --> CPD-14461 + UDP + PROTON
View More
Organism Source

Taxonomy Source

  1. Calycanthus praecox [ncbi taxid: ]
  2. Capparis decidua [ncbi taxid: 622458]
  3. Eucommia ulmoides [ncbi taxid: 4392]
  4. Psychotria klugii [ncbi taxid: ]
  5. Acacia cambagei [ncbi taxid: 1173637]
  6. Adina rubescens [ncbi taxid: ]
  7. Aesculus hippocastanum [ncbi taxid: 43364]
  8. Agave huachucensis [ncbi taxid: ]
  9. Allium victorialis [ncbi taxid: 88845]
  10. Aloe indica [ncbi taxid: ]
  11. Althaea officinalis [ncbi taxid: 145745]
  12. Angelica dahurica [ncbi taxid: 48101]
  13. Angiopteris caudatiformis [ncbi taxid: 397664]
  14. Aniba duckei [ncbi taxid: ]
  15. Anisomeles indica [ncbi taxid: 516069]
  16. Annona cherimolia [ncbi taxid: ]
  17. Anomospermum grandifolium [ncbi taxid: 461550]
  18. Arnica viscosa [ncbi taxid: 436215]
  19. Arthrobacter viscosus [ncbi taxid: ]
  20. Arthrophytum leptocladum [ncbi taxid: ]
  21. Aspidixia articulata [ncbi taxid: ]
  22. Aster alpinus [ncbi taxid: 669631]
  23. Athanasia dregeana [ncbi taxid: ]
  24. Baccharis solieri [ncbi taxid: ]
  25. Baptisia lecontii [ncbi taxid: ]
  26. Basanacantha spinosa [ncbi taxid: ]
  27. Berberis crataegina [ncbi taxid: 2602221]
  28. Bidens bipinnata [ncbi taxid: 1527831]
  29. Blepharis sindica [ncbi taxid: ]
  30. Bruguiera cylindrica [ncbi taxid: 106616]
  31. Bursaria spinosa [ncbi taxid: 105281]
  32. Calceolaria thyrsiflora [ncbi taxid: 240994]
  33. Calophyllum thwaitesii [ncbi taxid: ]
  34. Cellulomonas biazotea [ncbi taxid: 1709]
  35. Centaurea aemulans [ncbi taxid: ]
  36. Cercosporina kikuchii [ncbi taxid: ]
  37. Chlamydomonas reinhardtii [ncbi taxid: 3055]
  38. Cichorium glandulosum [ncbi taxid: 1405821]
  39. Cichorium intybus [ncbi taxid: 13427]
  40. Cladosporium tenuissimum [ncbi taxid: 70808]
  41. Clarkia unguiculata [ncbi taxid: 3937]
  42. Clinostemon mahuba [ncbi taxid: ]
  43. Conyza bonariensis [ncbi taxid: 91242]
  44. Coptis trifolia subsp. groenlandica [ncbi taxid: 1844482]
  45. Corbicula fluminea [ncbi taxid: 45949]
  46. Cortex fraxini [ncbi taxid: ]
  47. Crambe crambe [ncbi taxid: 3722]
  48. Crataegus pontica [ncbi taxid: ]
  49. Crataegus rhipidophylla [ncbi taxid: 510738]
  50. Crepidotus fulvotomentosus [ncbi taxid: ]
  51. Croton steenkampianus [ncbi taxid: 992676]
  52. Cryptocarya infectoria [ncbi taxid: ]
  53. Cynara scolymus [ncbi taxid: ]
  54. Dahlstedtia pinnata [ncbi taxid: 62116]
  55. Daphne aurantiaca [ncbi taxid: 2918710]
  56. Daphne papyracea [ncbi taxid: 2715869]
  57. Datura stramonium [ncbi taxid: 4076]
  58. Diaporthe amygdali [ncbi taxid: 1214568]
  59. Dichomitus squalens [ncbi taxid: 114155]
  60. Dictamnus gymnostylis [ncbi taxid: ]
  61. Durio oxleyanus [ncbi taxid: 117662]
  62. Ecbolium linneanum [ncbi taxid: ]
  63. Echinocystis lobata [ncbi taxid: 252533]
  64. Erinus alpinus [ncbi taxid: 165304]
  65. Erioderma chilense [ncbi taxid: ]
  66. Eriostemon brucei [ncbi taxid: ]
  67. Eriostemon crowei [ncbi taxid: ]
  68. Euphorbia lathyris [ncbi taxid: 212925]
  69. Felicia amelloides [ncbi taxid: 696374]
  70. Flemingia rhodocarpa [ncbi taxid: 1888369]
  71. Foeniculum vulgare [ncbi taxid: ]
  72. Fragaria indica [ncbi taxid: ]
  73. Fraxinus bungeana [ncbi taxid: 490836]
  74. Fraxinus chinensis [ncbi taxid: 56033]
  75. Fraxinus chinensis subsp. rhynchophylla [ncbi taxid: 126596]
  76. Fraxinus excelsior L. [ncbi taxid: ]
  77. Fraxinus mandshurica [ncbi taxid: 56029]
  78. Fraxinus ornus [ncbi taxid: 38874]
  79. Fraxinus paxiana [ncbi taxid: 490846]
  80. Fraxinus rhynchophylla [ncbi taxid: ]
  81. Fraxinus stylosa [ncbi taxid: 2291128]
  82. Fraxinus szaboana [ncbi taxid: ]
  83. Fritillaria taipaiensis [ncbi taxid: 152093]
  84. Frullania brittoniae [ncbi taxid: 642286]
  85. Fulmarus glacialis [ncbi taxid: 30455]
  86. Garcinia cantleyana [ncbi taxid: 469920]
  87. Geranium macrorrhizum [ncbi taxid: 28963]
  88. Gonepteryx rhamni [ncbi taxid: 78609]
  89. Guettarda eximia [ncbi taxid: ]
  90. Gypothamnium pinifolium [ncbi taxid: 540063]
  91. Haemanthus toxicarius [ncbi taxid: ]
  92. Helenium quadridentatum [ncbi taxid: 1448041]
  93. Heliconius cydno [ncbi taxid: 33424]
  94. Herba cichorii [ncbi taxid: ]
  95. Heterocapsa triquetra [ncbi taxid: ]
  96. Heteromma simplicifolium [ncbi taxid: ]
  97. Hymenodictyon excelsum [ncbi taxid: 640128]
  98. Hypolaena fastigiata [ncbi taxid: 1125853]
  99. Isodon gesneroides [ncbi taxid: 662912]
  100. Jacobaea arnautorum [ncbi taxid: 189245]
  101. Kalanchoe marmorata [ncbi taxid: 117969]
  102. Lactarius pubescens [ncbi taxid: 152943]
  103. Lamellodysidea herbacea [ncbi taxid: 279619]
  104. Latua pubiflora [ncbi taxid: 540810]
  105. Lobelia st [ncbi taxid: ]
  106. Lonicera korolkovii [ncbi taxid: ]
  107. Machilus robusta [ncbi taxid: 460780]
  108. Maclura aurantiaca [ncbi taxid: ]
  109. Manihot esculenta [ncbi taxid: 3983]
  110. Melaleuca decora [ncbi taxid: ]
  111. Melanothamnus somalensis [ncbi taxid: 1917069]
  112. Melilotus officinalis subsp. suaveolens [ncbi taxid: 74781]
  113. Melilotus suaveolens [ncbi taxid: ]
  114. Meryta denhamii [ncbi taxid: 126688]
  115. Micrococcus luteus [ncbi taxid: 1270]
  116. Mimosa invisa [ncbi taxid: 499990]
  117. Morinda citrifolia [ncbi taxid: 43522]
  118. Morus alba [ncbi taxid: 3498]
  119. Nama johnstonii [ncbi taxid: ]
  120. Nipaecoccus aurilanatus [ncbi taxid: ]
  121. Ophiocoma echinata [ncbi taxid: 331088]
  122. Paramignya griffithii [ncbi taxid: ]
  123. Parmelia gigas [ncbi taxid: ]
  124. Pedicularis densispica [ncbi taxid: 216516]
  125. Penianthus zenkeri [ncbi taxid: 2708930]
  126. Pentaceraster alveolatus [ncbi taxid: 1955718]
  127. Phebalium gracile [ncbi taxid: ]
  128. Phlomoides medicinalis [ncbi taxid: 1138144]
  129. Pinus densiflora var. densiflora [ncbi taxid: 1044906]
  130. Plantago uniflora [ncbi taxid: ]
  131. Podocarpus montanus [ncbi taxid: ]
  132. Polypodium hastatum [ncbi taxid: ]
  133. Polytolypa hystricis [ncbi taxid: 221428]
  134. Portulaca pilosa [ncbi taxid: 766930]
  135. Pseudomonas putida [ncbi taxid: 303]
  136. Pseudophegopteris subaurita [ncbi taxid: ]
  137. Pteris aquilina [ncbi taxid: ]
  138. Pteris inaequalis [ncbi taxid: 2815894]
  139. pterocaulon sp. [ncbi taxid: ]
  140. Randia longispina [ncbi taxid: ]
  141. Remijia pedunculata [ncbi taxid: ]
  142. Renilla muelleri [ncbi taxid: 37510]
  143. Rhododendron tomentosum [ncbi taxid: 49170]
  144. Rhodoglossum japonicum [ncbi taxid: ]
  145. Rhodopila globiformis [ncbi taxid: 1071]
  146. Roccellaria mollis [ncbi taxid: 415645]
  147. Rudbeckia hirta [ncbi taxid: 52299]
  148. Ruscus aculeatus [ncbi taxid: 59067]
  149. Saracha viscosa [ncbi taxid: ]
  150. Sarcodon aspratus [ncbi taxid: 155012]
  151. Schisandra arisanensis [ncbi taxid: 453241]
  152. Senecio macrophyllus [ncbi taxid: ]
  153. Senecio polyodon [ncbi taxid: 1892290]
  154. Senna sophera [ncbi taxid: 948718]
  155. Sinopodophyllum emodi [ncbi taxid: ]
  156. Solanum chacoense [ncbi taxid: 4108]
  157. Solanum toxicarum [ncbi taxid: ]
  158. Sophora davidii [ncbi taxid: 49839]
  159. Sophora japonica [ncbi taxid: ]
  160. Sophora secundiflora [ncbi taxid: ]
  161. Spongia australis [ncbi taxid: ]
  162. Stelletta inconspicua [ncbi taxid: ]
  163. Stenostomum acutatum [ncbi taxid: ]
  164. Symphytum tuberosum [ncbi taxid: 256504]
  165. Talaromyces helicus [ncbi taxid: 36628]
  166. Teucrium pernyi [ncbi taxid: ]
  167. Thymus magnus [ncbi taxid: 228975]
  168. Thymus transcaucasicus [ncbi taxid: 2019959]
  169. Trichia carnea [ncbi taxid: ]
  170. Trichia favoginea [ncbi taxid: ]
  171. Tricholoma batschii [ncbi taxid: 76321]
  172. Tulipa silvestris [ncbi taxid: ]
  173. Virola sebifera [ncbi taxid: 224866]
  174. Xanthoparmelia pokornyi [ncbi taxid: 164177]
  175. Xerula melanotricha [ncbi taxid: 302556]
  176. Xiphophora gladiata [ncbi taxid: 340368]
  177. Zerynthia polyxena [ncbi taxid: 330376]
  178. [polyangium] brachysporum [ncbi taxid: ]
  179. Aesculus hippocastanum [ncbi taxid: 43364]
  180. Bursaria spinosa [ncbi taxid: 105281]
  181. Cichorium intybus [ncbi taxid: 13427]
  182. Crataegus oxyacantha [ncbi taxid: ]
  183. Datura stramonium [ncbi taxid: 4076]
  184. Euphorbia lathyris [ncbi taxid: 212925]
  185. Ficus septica [ncbi taxid: 100573]
  186. Fraxinus bungeana [ncbi taxid: 490836]
  187. Fraxinus mandshurica [ncbi taxid: 56029]
  188. Fraxinus ornus [ncbi taxid: 38874]
  189. Fraxinus paxiana [ncbi taxid: 490846]
  190. Fraxinus rhynchophylla [ncbi taxid: ]
  191. Fraxinus spp. [ncbi taxid: ]
  192. Fraxinus stylosa [ncbi taxid: 2291128]
  193. Fraxinus szaboana [ncbi taxid: ]
  194. Hymenodictyon excelsum [ncbi taxid: 640128]
  195. Melilotus suaveolens [ncbi taxid: ]

Pathway Synthetic

pathway id name
BioCyc:META_PWY-7058 esculetin modification
BioCyc:META_PWY-7186 superpathway of scopolin and esculin biosynthesis
BioCyc:ARA_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:ALYRATA_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:SWITCHGRASS_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:ASPARAGUS_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:BANANA_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:BOLERACEA_CAPITATA_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:BRAPA_FPSC_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:BSTRICTA_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:CARIETINUM_ICC4958_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:SACREDLOTUS_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:COCOA_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:CROSEUS_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:CRUBELLA_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:CUCUMBER_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:EGGPLANT_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:OLONGISTAMINATA_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:FLAX_PWY-7186 superpathway of scopolin and esculin biosynthesis
PlantCyc:PIGEONPEA_PWY-7186 superpathway of scopolin and esculin biosynthesis
View All Pathways