(S)-Propane-1,2-diol (BioCAD00000001016)

saliva microbial natural products

Metabolite Card

Formula: C3H8O2 (76.0524)
SMILES: C[C@H](O)CO

Synonyms [en]

(S)-Propylene glycol; (S)-Propane-1,2-diol; (S)-1,2-Propanediol; (2S)-propane-1,2-diol; (S)-2-HYDROXYPROPANOL; (S)-(+)-Propylene Glycol

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

(S)-Propane-1,2-diol. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000001016). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

(S)-Propane-1,2-diol, also known as (S)-1,2-propanediol or (S)-propylene glycol, belongs to the class of organic compounds known as 1,2-diols. These are polyols containing an alcohol group at two adjacent positions. (S)-Propane-1,2-diol is an extremely weak basic (essentially neutral) compound (based on its pKa). (S)-Propane-1,2-diol has been detected, but not quantified in, several different foods, such as common buckwheats, mustard spinach, sugar apples, black crowberries, and bayberries. This could make (S)-propane-1,2-diol a potential biomarker for the consumption of these foods. (S)-Propane-1,2-diol is a clear, colourless, viscous organic solvent and diluent used in pharmaceutical preparations.

Cytoplasm
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 4254-15-3
  • PubChem: 439846
  • ChEBI: ChEBI:29002
  • HMDB: HMDB0006213
  • KEGG: C02917
  • BioCyc: PROPANE-1-2-DIOL
  • Wikipedia: Propylene_glycol
  • DrugBank: DB04349
  • Coconut NaturalProduct: CNP0522839.1

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R02258 1.1.1.77 (S)-propane-1,2-diol:NAD+ oxidoreductase
BioCyc:LACTALDREDUCT-RXN 1.1.1.77 PROPANE-1-2-DIOL + NAD<=>LACTALD + NADH + PROTON
BioCyc:RXN-8632 PROPANE-1-2-DIOL + NAD<=>ACETOL + NADH + PROTON
BioCyc:RXN-15744 1.1.1.55 LACTALD + NADPH + PROTON --> PROPANE-1-2-DIOL + NADP
Rhea:RHEA:15934 1.1.1.77 (S)-propane-1,2-diol + NAD+ => (S)-lactaldehyde + NADH + H+
Rhea:RHEA:15935 1.1.1.77 (S)-lactaldehyde + NADH + H+ => (S)-propane-1,2-diol + NAD+
Rhea:RHEA:15936 1.1.1.77 (S)-propane-1,2-diol + NAD+ <=> (S)-lactaldehyde + NADH + H+
Rhea:RHEA:28668 hydroxyacetone + NADH + H+ => (S)-propane-1,2-diol + NAD+
Rhea:RHEA:28669 (S)-propane-1,2-diol + NAD+ => hydroxyacetone + NADH + H+
Rhea:RHEA:28670 hydroxyacetone + NADH + H+ <=> (S)-propane-1,2-diol + NAD+
BioCyc:PROPANEDIOL-DEHYDRATASE-RXN 4.2.1.28 PROPANE-1-2-DIOL --> CPD-665 + WATER
BioCyc:RXN-22516 1.1.1.21 ACETOL + NADPH + PROTON --> PROPANE-1-2-DIOL + NADP
View More
Organism Source

Taxonomy Source

  1. Chaenomeles sinensis [ncbi taxid: ]
  2. Escherichia coli [ncbi taxid: 562]
  3. Homo sapiens [ncbi taxid: 9606]

Pathway Synthetic

pathway id name
BioCyc:HUMAN_PWY-5453 methylglyoxal degradation III
BioCyc:META_PWY-7013 (S)-propane-1,2-diol degradation
BioCyc:META_FUC-RHAMCAT-PWY superpathway of fucose and rhamnose degradation
BioCyc:ECO_PWY0-1315 L-lactaldehyde degradation (anaerobic)
BioCyc:ECO_PWY-5453 methylglyoxal degradation III
BioCyc:ECOO157_FUC-RHAMCAT-PWY superpathway of fucose and rhamnose degradation
BioCyc:ECOL199310_PWY-5453 methylglyoxal degradation III
BioCyc:ECOL199310_FUC-RHAMCAT-PWY superpathway of fucose and rhamnose degradation
BioCyc:ECOL199310_PWY0-1315 L-lactaldehyde degradation (anaerobic)
BioCyc:ECOL316407_FUC-RHAMCAT-PWY superpathway of fucose and rhamnose degradation
BioCyc:ECOL413997_PWY0-1315 L-lactaldehyde degradation (anaerobic)
BioCyc:ECOL413997_PWY-5453 methylglyoxal degradation III
BioCyc:CLOSSAC_PWY0-1315 L-lactaldehyde degradation (anaerobic)
BioCyc:CLOSSAC_FUC-RHAMCAT-PWY superpathway of fucose and rhamnose degradation
BioCyc:COLLINSAERO_PWY0-1315 L-lactaldehyde degradation (anaerobic)
BioCyc:ECO_METHGLYUT-PWY superpathway of methylglyoxal degradation
BioCyc:SHIGELLA_PWY0-1315 L-lactaldehyde degradation (anaerobic)
BioCyc:SHIGELLA_FUC-RHAMCAT-PWY superpathway of fucose and rhamnose degradation
BioCyc:ECOO157_PWY-5453 methylglyoxal degradation III
BioCyc:SCO_PWY0-1315 L-lactaldehyde degradation (anaerobic)
View All Pathways