EC: 4.1.1.32

phosphoenolpyruvate carboxykinase (GTP) (GTP:oxaloacetate carboxy-lyase (adding GTP; phosphoenolpyruvate-forming))

enzyme lambda metabolic reaction experiment
- [Mn2+]

Oxaloacetate + GTP -> Phosphoenolpyruvate + CO2 + GDP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Imidazole, 2.0 mM GSH
PH: 7.3
Temperature: 30
- [Mn2+]

Oxaloacetate + ITP -> Phosphoenolpyruvate + CO2 + IDP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Imidazole, 2.0 mM GSH
PH: 7.3
Temperature: 30
- [Mn2+]

ITP + Oxaloacetate -> CO2 + Phosphoenolpyruvate + IDP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Imidazole, 2.0 mM GSH
PH: 7.3
Temperature: 30
- [Mn2+]

ITP + Oxaloacetate -> CO2 + Phosphoenolpyruvate + IDP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-Cl, 2.0 mM GSH
PH: 7.3
Temperature: 30
- [Mn2+]

ITP + Oxaloacetate -> IDP + Phosphoenolpyruvate + CO2		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-Cl, 2.0 mM GSH
PH: 8
Temperature: 30
- [Mn2+]

ITP + Oxaloacetate -> CO2 + Phosphoenolpyruvate + IDP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Imidazole, 2.0 mM GSH
PH: 6.8
Temperature: 30
- [Mn2+]

CO2 + GDP + Phosphoenolpyruvate -> Oxaloacetate + GTP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Imidazole, 2.0 mM GSH, 2.5 mM NADH, 1-5 U/ml Malate dehydrogenase
PH: 7.1
Temperature: 30
- [Mn2+]

Phosphoenolpyruvate + IDP + CO2 -> ITP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-Cl, 2.0 mM GSH, 2.5 mM NADH, 1-5 U/ml Malate dehydrogenase
PH: 7.5
Temperature: 30
- [Mn2+]

CO2 + IDP + Phosphoenolpyruvate -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Imidazole, 2.0 mM GSH, 2.5 mM NADH, 1-5 U/ml Malate dehydrogenase
PH: 7.1
Temperature: 30
- [Mn2+]

Phosphoenolpyruvate + IDP + CO2 -> ITP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Imidazole, 2.0 mM GSH, 2.5 mM NADH, 1-5 U/ml Malate dehydrogenase
PH: 7.1
Temperature: 30
- [Mn2+]

CO2 + IDP + Phosphoenolpyruvate -> ITP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-Cl, 2.0 mM GSH, 2.5 mM NADH, 1-5 U/ml Malate dehydrogenase
PH: 7.58
Temperature: 30
- [Mn2+]

CO2 + IDP + Phosphoenolpyruvate -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-Cl, 2.0 mM GSH, 2.5 mM NADH, 1-5 U/ml Malate dehydrogenase
PH: 7.55
Temperature: 30
- [Mn2+]

Phosphoenolpyruvate + CO2 + IDP -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-Cl, 2.0 mM GSH, 2.5 mM NADH, 1-5 U/ml Malate dehydrogenase
PH: 7.5
Temperature: 30
- [Mn2+]

Phosphoenolpyruvate + CO2 + IDP -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-Cl, 2.0 mM GSH, 2.5 mM NADH, 1-5 U/ml Malate dehydrogenase
PH: 7.5
Temperature: 30
- [Mn2+]

IDP + Phosphoenolpyruvate + CO2 -> ITP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-Cl, 2.0 mM GSH, 2.5 mM NADH, 1-5 U/ml Malate dehydrogenase
PH: 7.55
Temperature: 30
- [Mn2+]

Oxaloacetate + GTP -> Phosphoenolpyruvate + GDP + CO2		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Imidazole, 2.0 mM GSH
PH: 6.8
Temperature: 30
- [Mn2+]

Oxaloacetate + GTP -> Phosphoenolpyruvate + GDP + CO2		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-Cl, 1.0 mM MgCl2, 2.0 mM GSH, 0.15 mM NADH, 1.2 U/ml Pyruvate kinase, 2.5 U/ml Lactate dehydrogenase
PH: 7.45
Temperature: 30
- [Mn2+]

Oxaloacetate + ITP -> Phosphoenolpyruvate + CO2 + IDP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Imidazole, 2.0 mM GSH
PH: 6.8
Temperature: 30
- [Mn2+]

Oxaloacetate + ITP -> Phosphoenolpyruvate + IDP + CO2		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Imidazole, 2.0 mM GSH
PH: 6.8
Temperature: 30
- [Mn2+]

ITP + Oxaloacetate -> IDP + Phosphoenolpyruvate + CO2		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Imidazole, 2.0 mM GSH
PH: 7.3
Temperature: 30
- [Mn2+]

ITP + Oxaloacetate -> Phosphoenolpyruvate + IDP + CO2		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-Cl, 1.0 mM MgCl2, 2.0 mM GSH, 0.15 mM NADH, 1.2 U/ml Pyruvate kinase, 2.5 U/ml Lactate dehydrogenase
PH: 7.45
Temperature: 30
- [Mn2+]

Oxaloacetate + ITP -> IDP + Phosphoenolpyruvate + CO2		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-Cl, 1.0 mM MgCl2, 2.0 mM GSH, 0.15 mM NADH, 1.2 U/ml Pyruvate kinase, 2.5 U/ml Lactate dehydrogenase
PH: 7.45
Temperature: 30
- [Mn2+]

Oxaloacetate + ITP -> CO2 + IDP + Phosphoenolpyruvate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-Cl, 1.0 mM MgCl2, 2.0 mM GSH, 0.15 mM NADH, 1.2 U/ml Pyruvate kinase, 2.5 U/ml Lactate dehydrogenase
PH: 7.45
Temperature: 30
uniprot:P21642 [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

IDP + CO2 + Phosphoenolpyruvate -> ITP + Oxaloacetate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: MES or HEPES or Tris or TAPS, 60 µM MnCl2, 4 mM MgCl2
PH: 6.25
Temperature: 25
uniprot:P21642 [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

Phosphoenolpyruvate + CO2 + IDP -> Oxaloacetate + ITP		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: MES or HEPES or Tris or TAPS, 60 µM MnCl2, 4 mM MgCl2
PH: 6.25
Temperature: 25
uniprot:P21642 [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

Phosphoenolpyruvate + IDP + CO2 -> ITP + Oxaloacetate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: MES or HEPES or Tris or TAPS, 60 µM MnCl2, 4 mM MgCl2
PH: 6.25
Temperature: 25
- [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

GDP + Phosphoenolpyruvate + CO2 -> GTP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 1 mM MnCl2, 0.05 mM NADH, 17 mM NaHCO3, 2 U/ml malate dehydrogenase, 2 µg/ml rotenone
PH: 7.4
Temperature: 25
- [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

CO2 + IDP + Phosphoenolpyruvate -> ITP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 1 mM MnCl2, 0.05 mM NADH, 17 mM NaHCO3, 2 U/ml malate dehydrogenase, 2 µg/ml rotenone
PH: 7.4
Temperature: 25
- [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

CO2 + XDP + Phosphoenolpyruvate -> XTP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 1 mM MnCl2, 0.05 mM NADH, 17 mM NaHCO3, 2 U/ml malate dehydrogenase, 2 µg/ml rotenone
PH: 7.4
Temperature: 25
- [Mg2+]

GDP + CO2 + Phosphoenolpyruvate -> Oxaloacetate + GTP		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M HEPES, 0.2 mM NADH, 1 mM DTT, 2 µM EDTA, 42 units/ml Malate dehydrogenase
PH: 7.2
Temperature: 26
- [Mg2+]

Phosphoenolpyruvate + GDP + CO2 -> Oxaloacetate + GTP		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M HEPES, 0.2 mM NADH, 1 mM DTT, 2 µM EDTA, 42 units/ml Malate dehydrogenase
PH: 7.2
Temperature: 26
- [Mg2+]

Phosphoenolpyruvate + GDP + CO2 -> GTP + Oxaloacetate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M HEPES, 0.2 mM NADH, 1 mM DTT, 2 µM EDTA, 42 units/ml Malate dehydrogenase
PH: 7.2
Temperature: 26
- [Mg2+]

CO2 + GDP + Phosphoenolpyruvate -> GTP + Oxaloacetate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M HEPES, 0.2 mM NADH, 1 mM DTT, 2 µM EDTA, 42 units/ml Malate dehydrogenase
PH: 7.2
Temperature: 26
- [Mg2+]

CO2 + GDP + Phosphoenolpyruvate -> GTP + Oxaloacetate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M HEPES, 0.2 mM NADH, 1 mM DTT, 2 µM EDTA, 42 units/ml Malate dehydrogenase
PH: 7.2
Temperature: 26
- [Mg2+]

CO2 + GDP + Phosphoenolpyruvate -> Oxaloacetate + GTP		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M HEPES, 0.2 mM NADH, 1 mM DTT, 2 µM EDTA, 42 units/ml Malate dehydrogenase
PH: 7.2
Temperature: 26
- [Mg2+]

CO2 + Phosphoenolpyruvate + GDP -> Oxaloacetate + GTP		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M HEPES, 0.2 mM NADH, 1 mM DTT, 2 µM EDTA, 42 units/ml Malate dehydrogenase
PH: 7.2
Temperature: 26
- [Mg2+]

GDP + CO2 + Phosphoenolpyruvate -> GTP + Oxaloacetate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M HEPES, 0.2 mM NADH, 1 mM DTT, 2 µM EDTA, 42 units/ml Malate dehydrogenase
PH: 7.2
Temperature: 26
- [Mg2+]

Phosphoenolpyruvate + GDP + CO2 -> GTP + Oxaloacetate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M HEPES, 0.2 mM NADH, 1 mM DTT, 2 µM EDTA, 42 units/ml Malate dehydrogenase
PH: 7.2
Temperature: 26
- [Mg2+]

CO2 + GDP + Phosphoenolpyruvate -> GTP + Oxaloacetate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M HEPES, 0.2 mM NADH, 1 mM DTT, 2 µM EDTA, 42 units/ml Malate dehydrogenase
PH: 7.2
Temperature: 26
- [Mg2+]

CO2 + GDP + Phosphoenolpyruvate -> Oxaloacetate + GTP		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M HEPES, 0.2 mM NADH, 1 mM DTT, 2 µM EDTA, 42 units/ml Malate dehydrogenase
PH: 7.2
Temperature: 26
- [Mg2+]

GDP + CO2 + Phosphoenolpyruvate -> Oxaloacetate + GTP		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M HEPES, 0.2 mM NADH, 1 mM DTT, 2 µM EDTA, 42 units/ml Malate dehydrogenase
PH: 7.2
Temperature: 26
- [Mg2+]

Phosphoenolpyruvate + CO2 + GDP -> Oxaloacetate + GTP		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M HEPES, 0.2 mM NADH, 1 mM DTT, 2 µM EDTA, 42 units/ml Malate dehydrogenase
PH: 7.2
Temperature: 26
uniprot:Q9AGJ6 [1,4-Dithiothreitol]

IDP + CO2 + Phosphoenolpyruvate -> ITP + Oxaloacetate		 (( (Vmax * A) ) / (( (Km * (1 + (I / Kis))) ) + (A * (1 + (I / Kii))))) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [1,4-Dithiothreitol]

Phosphoenolpyruvate + IDP + CO2 -> ITP + Oxaloacetate		 (( (Vmax * A) ) / (( (Km * (1 + (I / Kis))) ) + (A * (1 + (I / Kii))))) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [1,4-Dithiothreitol]

CO2 + GDP + Phosphoenolpyruvate -> Oxaloacetate + GTP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [1,4-Dithiothreitol]

GTP + Oxaloacetate -> GDP + CO2 + Phosphoenolpyruvate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 3 mM Malate, 1 mM NAD+, 6 units/ml Malate dehydrogenase from Thermus flavus
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [1,4-Dithiothreitol]

GTP + Oxaloacetate -> CO2 + GDP + Phosphoenolpyruvate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 3 mM Malate, 1 mM NAD+, 6 units/ml Malate dehydrogenase from Thermus flavus
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [1,4-Dithiothreitol]

Phosphoenolpyruvate + CO2 + IDP -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [1,4-Dithiothreitol]

Phosphoenolpyruvate + IDP + CO2 -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [Co2+]

GDP + CO2 + Phosphoenolpyruvate -> Oxaloacetate + GTP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [1,4-Dithiothreitol]

IDP + CO2 + Phosphoenolpyruvate -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [Mg2+]

Phosphoenolpyruvate + CO2 + IDP -> ITP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [Co2+]

IDP + CO2 + Phosphoenolpyruvate -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [1,4-Dithiothreitol]

GDP + Phosphoenolpyruvate + CO2 -> Oxaloacetate + GTP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [Mg2+]

CO2 + Phosphoenolpyruvate + GDP -> GTP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [1,4-Dithiothreitol]

Phosphoenolpyruvate + CO2 + IDP -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [1,4-Dithiothreitol]

Phosphoenolpyruvate + IDP + CO2 -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [1,4-Dithiothreitol]

IDP + Phosphoenolpyruvate + CO2 -> ITP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [Mg2+]

Phosphoenolpyruvate + CO2 + IDP -> ITP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [Co2+]

Phosphoenolpyruvate + IDP + CO2 -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [Mn2+]

Phosphoenolpyruvate + CO2 + IDP -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
uniprot:Q9AGJ6 [Co2+]

IDP + CO2 + Phosphoenolpyruvate -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 2 units/ml Malate dehydrogenase from Thermus flavus, 0.25 mM NADH
PH: 7.2
Temperature: 37
- [Mn2+]

GTP + Oxaloacetate -> GDP + CO2 + Phosphoenolpyruvate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM MES-NaOH, 50 mM KHCO3, 4.0 mM MgCl2, 0.15 mM NADH, 1.0 IU malate dehydrogenase
PH: 6
Temperature: 37
- [Mn2+]

GTP + Oxaloacetate -> CO2 + GDP + Phosphoenolpyruvate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM MES-NaOH, 50 mM KHCO3, 4.0 mM MgCl2, 0.15 mM NADH, 1.0 IU malate dehydrogenase
PH: 6
Temperature: 37
uniprot:P07379 [Mn2+]

Oxaloacetate + ITP -> CO2 + Phosphoenolpyruvate + IDP		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM imidazole, 1 mM NAD+, 1 U/ml malate dehyrdogenase
PH: 7
Temperature: 37
uniprot:P07379 [Mn2+]

Oxaloacetate + ITP -> Phosphoenolpyruvate + CO2 + IDP		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM Imidazole, 1 mM GSH
PH: 7
Temperature: 37
uniprot:P07379 [Mg2+]

ITP + Oxaloacetate -> Phosphoenolpyruvate + CO2 + IDP		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM Imidazole, 1 mM GSH
PH: 7
Temperature: 37
- [Mn2+]

Oxaloacetate + ITP -> IDP + Phosphoenolpyruvate + CO2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM Imidazole, 1 mM GSH
PH: 7
Temperature: 37
- [Mn2+]

Oxaloacetate + ITP -> Phosphoenolpyruvate + IDP + CO2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM Imidazole, 1 mM GSH
PH: 7
Temperature: 37
- [Mg2+]

Oxaloacetate + ITP -> IDP + Phosphoenolpyruvate + CO2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM Imidazole, 1 mM GSH
PH: 7
Temperature: 37
uniprot:P07379 [IDP]

Oxaloacetate -> CO2 + Pyruvate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM imidazole, 1 mM NAD+, 1 U/ml malate dehyrdogenase
PH: 7
Temperature: 37
uniprot:P21642 [Mn2+]

Oxaloacetate + ITP -> CO2 + Phosphoenolpyruvate + IDP		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM Imidazole, 1 mM GSH
PH: 7
Temperature: 37
uniprot:P21642 [Mg2+]

ITP + Oxaloacetate -> CO2 + Phosphoenolpyruvate + IDP		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM Imidazole, 1 mM GSH
PH: 7
Temperature: 37
- [Mg2+]

ITP + Oxaloacetate -> CO2 + Phosphoenolpyruvate + IDP		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM Imidazole, 1 mM GSH
PH: 7
Temperature: 37
uniprot:P21642 [Mn2+]

CO2 + Phosphoenolpyruvate + IDP -> ITP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 65 mM Tris Acetate, 100 mM KCl, 143 mM beta-Mercaptoethanol, 0.14 mM NADH, 22 U/ml malate dehydrogenase
PH: 7.5
Temperature: 25
uniprot:P21642 [Mn2+]

Phosphoenolpyruvate + GDP + CO2 -> GTP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 65 mM Tris Acetate, 100 mM KCl, 143 mM beta-Mercaptoethanol, 0.14 mM NADH, 22 U/ml malate dehydrogenase
PH: 7.5
Temperature: 25
uniprot:P21642 [Mn2+]

GDP + CO2 + Phosphoenolpyruvate -> GTP + Oxaloacetate		 (( (Vmax * M) ) / (Km + M)) buffer: 65 mM Tris Acetate, 100 mM KCl, 143 mM beta-Mercaptoethanol, 0.14 mM NADH, 22 U/ml malate dehydrogenase
PH: 7.5
Temperature: 25
uniprot:P21642 [Mn2+]

IDP + CO2 + Phosphoenolpyruvate -> ITP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 65 mM Tris Acetate, 100 mM KCl, 143 mM beta-Mercaptoethanol, 0.14 mM NADH, 22 U/ml malate dehydrogenase
PH: 7.5
Temperature: 25
uniprot:P21642 [Mn2+]

CO2 + IDP + Phosphoenolpyruvate -> Oxaloacetate + ITP		 (( (Vmax * M) ) / (Km + M)) buffer: 65 mM Tris Acetate, 100 mM KCl, 143 mM beta-Mercaptoethanol, 0.14 mM NADH, 22 U/ml malate dehydrogenase
PH: 7.5
Temperature: 25
uniprot:P21642 [Mn2+]

CO2 + IDP + Phosphoenolpyruvate -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (Km + A)) buffer: 65 mM Tris Acetate, 100 mM KCl, 143 mM beta-Mercaptoethanol, 0.14 mM NADH, 22 U/ml malate dehydrogenase
PH: 7.5
Temperature: 25
uniprot:P21642 [Mn2+]

ITP + Oxaloacetate -> CO2 + Phosphoenolpyruvate + IDP		 (( (Vmax * A) ) / (Km + A)) buffer: 65 mM Tris Acetate, 1 mM ADP, 100 mM KCl, 1.0 mM MgCl2, 0.21 mM NADH, 3 U/ml pyruvate kinase, 11.0 U/ml lactate dehydrogenase
PH: 7.4
Temperature: 25
uniprot:P21642 [Mn2+]

Phosphoenolpyruvate + CO2 + IDP -> ITP + Oxaloacetate		 (( (Vmax * M) ) / (Km + M)) buffer: 65 mM Tris Acetate, 100 mM KCl, 143 mM beta-Mercaptoethanol, 0.14 mM NADH, 22 U/ml malate dehydrogenase
PH: 7.5
Temperature: 25
uniprot:P21642 [Mn2+]

ITP + Oxaloacetate -> IDP + Phosphoenolpyruvate + CO2		 (( (Vmax * M) ) / (Km + M)) buffer: 65 mM Tris Acetate, 1 mM ADP, 100 mM KCl, 1.0 mM MgCl2, 0.21 mM NADH, 3 U/ml pyruvate kinase, 11.0 U/ml lactate dehydrogenase
PH: 7.4
Temperature: 25
uniprot:P21642 [Mn2+]

Oxaloacetate + ITP -> IDP + Phosphoenolpyruvate + CO2		 (( (Vmax * A) ) / (Km_app + A)) buffer: 65 mM Tris Acetate, 1 mM ADP, 100 mM KCl, 1.0 mM MgCl2, 0.21 mM NADH, 3 U/ml pyruvate kinase, 11.0 U/ml lactate dehydrogenase
PH: 7.4
Temperature: 25
uniprot:P21642 [alpha-(Dihydroxyphosphinylmethyl)acrylate]

CO2 + Phosphoenolpyruvate + IDP -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 65 mM Tris Acetate, 100 mM KCl, 143 mM beta-Mercaptoethanol, 0.14 mM NADH, 22 U/ml malate dehydrogenase
PH: 7.5
Temperature: 25
uniprot:P21642 [Mn2+]

CO2 + Phosphoenolpyruvate + IDP -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (( (Km * (1 + (I / Ki))) ) + (A * (1 + (I / Ki))))) buffer: 65 mM Tris Acetate, 100 mM KCl, 143 mM beta-Mercaptoethanol, 0.14 mM NADH, 22 U/ml malate dehydrogenase
PH: 7.5
Temperature: 25
uniprot:P21642 [Mn2+]

IDP + Phosphoenolpyruvate + CO2 -> Oxaloacetate + ITP		 (( (Vmax * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 65 mM Tris Acetate, 100 mM KCl, 143 mM beta-Mercaptoethanol, 0.14 mM NADH, 22 U/ml malate dehydrogenase
PH: 7.5
Temperature: 25
uniprot:P21642 [L-Phospholactate]

CO2 + Phosphoenolpyruvate + IDP -> ITP + Oxaloacetate		 (( (Vmax * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 65 mM Tris Acetate, 100 mM KCl, 143 mM beta-Mercaptoethanol, 0.14 mM NADH, 22 U/ml malate dehydrogenase
PH: 7.5
Temperature: 25
uniprot:P21642 [D-Phospholactate]

IDP + Phosphoenolpyruvate + CO2 -> ITP + Oxaloacetate		 (( (Vmax * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 65 mM Tris Acetate, 100 mM KCl, 143 mM beta-Mercaptoethanol, 0.14 mM NADH, 22 U/ml malate dehydrogenase
PH: 7.5
Temperature: 25
uniprot:P21642 [Mn2+]

Phosphoenolpyruvate + IDP + CO2 -> ITP + Oxaloacetate		 (Vmax / (1 + (( (( (Ks * Ka1) ) / (M * S)) ) * (( (1 + (M / Ka)) ) + (S / Ks))))) buffer: 65 mM Tris Acetate, 100 mM KCl, 143 mM beta-Mercaptoethanol, 0.14 mM NADH, 22 U/ml malate dehydrogenase
PH: 7.5
Temperature: 25
uniprot:P21642 [Mn2+]

IDP + CO2 + (Z)_3_Fluoro_phosphoenolpyruvate -> 3_Fluorooxaloacetate + ITP		 (( (Vmax * A) ) / (Km + A)) buffer: 65 mM Tris Acetate, 100 mM KCl, 143 mM beta-Mercaptoethanol, 0.14 mM NADH, 22 U/ml malate dehydrogenase
PH: 7.5
Temperature: 25
uniprot:P21642 [Mn2+]

IDP + CO2 + 3_Fluoro_phosphoenolpyruvate -> 3_Fluorooxaloacetate + ITP		 (( (Vmax * A) ) / (Km + A)) buffer: 65 mM Tris Acetate, 100 mM KCl, 143 mM beta-Mercaptoethanol, 0.14 mM NADH, 22 U/ml malate dehydrogenase
PH: 7.5
Temperature: 25
- [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

CO2 + GDP + Phosphoenolpyruvate -> Oxaloacetate + GTP		 (( (( (E * kcat) ) * CO2) ) / (Km + CO2)) buffer: 250 mM imidazole, 10 mM MnCl2, 10 mM NADH, 360 U/ml malate dehydrogenase, 10 mM 2-mercaptoethanol
PH: 6.3
Temperature: 37
- [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

CO2 + Phosphoenolpyruvate + GDP -> GTP + Oxaloacetate		 (( (( (E * kcat) ) * CO2) ) / (Km + CO2)) buffer: 250 mM imidazole, 10 mM MnCl2, 10 mM NADH, 360 U/ml malate dehydrogenase, 10 mM 2-mercaptoethanol
PH: 7.2
Temperature: 37
- [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

CO2 + Phosphoenolpyruvate + GDP -> Oxaloacetate + GTP		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 250 mM imidazole, 10 mM MnCl2, 10 mM NADH, 360 U/ml malate dehydrogenase, 10 mM 2-mercaptoethanol
PH: 7.2
Temperature: 37
- [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

GDP + CO2 + Phosphoenolpyruvate -> Oxaloacetate + GTP		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 250 mM imidazole, 10 mM MnCl2, 10 mM NADH, 360 U/ml malate dehydrogenase, 10 mM 2-mercaptoethanol
PH: 6.3
Temperature: 37
- [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

GTP + Oxaloacetate -> GDP + Phosphoenolpyruvate + CO2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 200 mM imidazole, 10 mM 2-mercaptoethanol, 10 mM MnCl2
PH: 7.2
Temperature: 37
- [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

GTP + Oxaloacetate -> GDP + CO2 + Phosphoenolpyruvate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 200 mM imidazole, 10 mM 2-mercaptoethanol, 10 mM MnCl2
PH: 7.2
Temperature: 37
- [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

Oxaloacetate + ITP -> IDP + CO2 + Phosphoenolpyruvate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 200 mM imidazole, 10 mM 2-mercaptoethanol, 10 mM MnCl2
PH: 7.2
Temperature: 37
- [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

Phosphoenolpyruvate + CO2 + GDP -> GTP + Oxaloacetate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 250 mM imidazole, 10 mM MnCl2, 10 mM NADH, 360 U/ml malate dehydrogenase, 10 mM 2-mercaptoethanol
PH: 6.3
Temperature: 37
- [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

Phosphoenolpyruvate + GDP + CO2 -> GTP + Oxaloacetate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 250 mM imidazole, 10 mM MnCl2, 10 mM NADH, 360 U/ml malate dehydrogenase, 10 mM 2-mercaptoethanol
PH: 7.2
Temperature: 37
- [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

Phosphoenolpyruvate + CO2 + IDP -> ITP + Oxaloacetate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 250 mM imidazole, 10 mM MnCl2, 10 mM NADH, 360 U/ml malate dehydrogenase, 10 mM 2-mercaptoethanol
PH: 6.3
Temperature: 37
- [phosphoenolpyruvate carboxykinase (GTP)(Enzyme) wildtype]

Phosphoenolpyruvate + CO2 + IDP -> ITP + Oxaloacetate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 250 mM imidazole, 10 mM MnCl2, 10 mM NADH, 360 U/ml malate dehydrogenase, 10 mM 2-mercaptoethanol
PH: 7.2
Temperature: 37
uniprot:P35558 [Mg2+]

CO2 + GDP + Phosphoenolpyruvate -> Oxaloacetate + GTP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 10 mM DTT, 0.2 mM NADH, 2 U/ml malate dehydrogenase
PH: 7.2
Temperature: 37
uniprot:P35558 [Mg2+]

Phosphoenolpyruvate + CO2 + GDP -> GTP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 10 mM DTT, 0.2 mM NADH, 2 U/ml malate dehydrogenase
PH: 7.2
Temperature: 37
uniprot:P35558 [Mg2+]

GDP + Phosphoenolpyruvate + CO2 -> Oxaloacetate + GTP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 10 mM DTT, 0.2 mM NADH, 2 U/ml malate dehydrogenase
PH: 7.2
Temperature: 37
uniprot:P35558 [Mg2+]

Phosphoenolpyruvate + CO2 + GDP -> GTP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 10 mM DTT, 0.2 mM NADH, 2 U/ml malate dehydrogenase
PH: 7.2
Temperature: 37
uniprot:P35558 [Mg2+]

CO2 + Phosphoenolpyruvate + GDP -> GTP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 10 mM DTT, 0.2 mM NADH, 2 U/ml malate dehydrogenase
PH: 7.2
Temperature: 37
uniprot:P35558 [Mg2+]

Oxaloacetate + GTP -> Phosphoenolpyruvate + CO2 + GDP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 3.6 mM L-malate, 10 mM DTT, 1 mM NAD+, 6 U/ml malate dehydrogenase
PH: 8
Temperature: 37
uniprot:P35558 [Mg2+]

GTP + Oxaloacetate -> GDP + CO2 + Phosphoenolpyruvate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 3.6 mM L-malate, 10 mM DTT, 1 mM NAD+, 6 U/ml malate dehydrogenase
PH: 8
Temperature: 37
uniprot:P35558 [Mg2+]

GTP + Oxaloacetate -> CO2 + Phosphoenolpyruvate + GDP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 3.6 mM L-malate, 10 mM DTT, 1 mM NAD+, 6 U/ml malate dehydrogenase
PH: 8
Temperature: 37
uniprot:P35558 [Mg2+]

GDP + Phosphoenolpyruvate + CO2 -> Oxaloacetate + GTP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 10 mM DTT, 0.2 mM NADH, 2 U/ml malate dehydrogenase
PH: 7.2
Temperature: 37
uniprot:P07379 [Mn2+]

GTP + Oxaloacetate -> GDP + CO2 + Phosphoenolpyruvate		 (( (Vmax * A) ) / (( (Ka * (1 + (I / Kis))) ) + (A * (1 + (I / Kii))))) buffer: 50 mM Tris-HCl, 1 mM NAD+, 3 U/ml malate dehydrogenase
PH: 8
Temperature: 37
uniprot:P07379 [Mn2+]

GTP + Oxaloacetate -> CO2 + GDP + Phosphoenolpyruvate		 (( (Vmax * A) ) / (( (Ka * (1 + (I / Kis))) ) + (A * (1 + (I / Kii))))) buffer: 0.2 M Tris-HCl, 1 mM NAD+, 3 U/ml malate dehydrogenase
PH: 8
Temperature: 37
uniprot:P07379 [Mn2+]

Oxaloacetate + GTP -> CO2 + Phosphoenolpyruvate + GDP		 (( (Vmax * A) ) / (( (Ka * (1 + (I / Kis))) ) + (A * (1 + (I / Kii))))) buffer: 50 mM Tris-HCl, 1 mM NAD+, 3 U/ml malate dehydrogenase
PH: 8
Temperature: 37
uniprot:P07379 [Mn2+]

Oxaloacetate + GTP -> CO2 + Phosphoenolpyruvate + GDP		 (( (( (Vmax * A) ) * B) ) / (( (( (( (Kia * Kb) ) + (Kb * A)) ) + (Ka * B)) ) + (A * B))) buffer: 50 mM Tris-HCl, 1 mM NAD+, 3 U/ml malate dehydrogenase
PH: 8
Temperature: 37
uniprot:P35558 [Mn2+]

GDP + Phosphoenolpyruvate + CO2 -> Oxaloacetate + GTP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 10 mM DTT, 0.2 mM NADH, 2 U/ml malate dehydrogenase
PH: 7.2
Temperature: 37
uniprot:P35558 [Mg2+]

Phosphoenolpyruvate + GDP + CO2 -> Oxaloacetate + GTP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 10 mM DTT, 0.2 mM NADH, 2 U/ml malate dehydrogenase
PH: 7.2
Temperature: 37
uniprot:P07379 [Mn2+]

Oxaloacetate + GTP -> Phosphoenolpyruvate + CO2 + GDP		 (( (Vmax * A) ) / (( (Ka * (1 + (I / Kis))) ) + (A * (1 + (I / Kii))))) buffer: 50 mM Tris-HCl, 1 mM NAD+, 3 U/ml malate dehydrogenase
PH: 8
Temperature: 37
uniprot:P07379 [Mn2+]

Oxaloacetate + GTP -> GDP + Phosphoenolpyruvate + CO2		 (( (Vmax * A) ) / (( (Ka * (1 + (I / Kis))) ) + (A * (1 + (I / Kii))))) buffer: 50 mM Tris-HCl, 1 mM NAD+, 3 U/ml malate dehydrogenase
PH: 8
Temperature: 37
uniprot:P07379 [Mn2+]

Oxaloacetate + GTP -> GDP + Phosphoenolpyruvate + CO2		 (( (Vmax * A) ) / (( (Ka * (1 + (I / Kis))) ) + (A * (1 + (I / Kii))))) buffer: 0.2 M Tris-HCl, 1 mM NAD+, 3 U/ml malate dehydrogenase
PH: 8
Temperature: 37
uniprot:P35558 [Mg2+]

Phosphoenolpyruvate + CO2 + GDP -> GTP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 10 mM DTT, 0.2 mM NADH, 2 U/ml malate dehydrogenase
PH: 7.2
Temperature: 37
uniprot:P35558 [Mg2+]

GDP + Phosphoenolpyruvate + CO2 -> Oxaloacetate + GTP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 10 mM DTT, 0.2 mM NADH, 2 U/ml malate dehydrogenase
PH: 7.2
Temperature: 37
uniprot:P35558 [Mg2+]

CO2 + GDP + Phosphoenolpyruvate -> GTP + Oxaloacetate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 10 mM DTT, 0.2 mM NADH, 2 U/ml malate dehydrogenase
PH: 7.2
Temperature: 37
uniprot:P35558 [Mg2+]

GTP + Oxaloacetate -> Phosphoenolpyruvate + CO2 + GDP		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 3.6 mM L-malate, 10 mM DTT, 1 mM NAD+, 6 U/ml malate dehydrogenase
PH: 8
Temperature: 37
uniprot:P35558 [Mg2+]

GTP + Oxaloacetate -> GDP + Phosphoenolpyruvate + CO2		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 3.6 mM L-malate, 10 mM DTT, 1 mM NAD+, 6 U/ml malate dehydrogenase
PH: 8
Temperature: 37
uniprot:P35558 [Mg2+]

GTP + Oxaloacetate -> GDP + CO2 + Phosphoenolpyruvate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM HEPES-NaOH, 3.6 mM L-malate, 10 mM DTT, 1 mM NAD+, 6 U/ml malate dehydrogenase
PH: 8
Temperature: 37

Pathways

pathway id name
BioCyc:HUMAN_PWY66-399 gluconeogenesis
BioCyc:META_PWY-7389 superpathway of anaerobic energy metabolism (invertebrates)
BioCyc:META_PWY-7383 anaerobic energy metabolism (invertebrates, cytosol)
BioCyc:META_PWY66-399 gluconeogenesis III
Reactome:R-HSA-9632974 LXRs regulate gene expression linked to gluconeogenesis
Reactome:R-HSA-9024446 LXR-mediated signaling
Reactome:R-HSA-9843745 Adipogenesis
Reactome:R-HSA-9748784 Drug ADME
Reactome:R-HSA-9614085 FOXO-mediated transcription
Reactome:R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Reactome:R-DDI-70263 Gluconeogenesis
Reactome:R-DME-71387 Carbohydrate metabolism
Reactome:R-DME-70326 Glucose metabolism
Reactome:R-GGA-1660598 Metabolism
Reactome:R-GGA-352875 Gluconeogenesis
Reactome:R-HSA-70263 Gluconeogenesis
Reactome:R-HSA-74160 Gene expression (Transcription)
Reactome:R-HSA-73857 RNA Polymerase II Transcription
Reactome:R-MMU-1430728 Metabolism
Reactome:R-DDI-71387 Carbohydrate metabolism
Reactome:R-DDI-70326 Glucose metabolism
Reactome:R-DME-1430728 Metabolism
Reactome:R-HSA-1266738 Developmental Biology
Reactome:R-HSA-71387 Carbohydrate metabolism
Reactome:R-HSA-70326 Glucose metabolism
Reactome:R-HSA-2161522 Abacavir ADME
Reactome:R-HSA-9006931 Signaling by Nuclear Receptors
Reactome:R-RNO-70263 Gluconeogenesis
Reactome:R-DME-70263 Gluconeogenesis
Reactome:R-GGA-353098 Carbohydrate metabolism
Reactome:R-HSA-381340 Transcriptional regulation of white adipocyte differentiation
Reactome:R-HSA-2161541 Abacavir metabolism
Reactome:R-HSA-212436 Generic Transcription Pathway
Reactome:R-MMU-71387 Carbohydrate metabolism
Reactome:R-MMU-70326 Glucose metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-DDI-1430728 Metabolism
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-162582 Signaling Pathways
Reactome:R-MMU-70263 Gluconeogenesis
Reactome:R-RNO-71387 Carbohydrate metabolism
Reactome:R-RNO-70326 Glucose metabolism
WikiPathways:WP5381 Smith-Magenis and Potocki-Lupski syndrome copy number variation
PathBank:SMP0120726 Leigh Syndrome
PathBank:SMP0120842 Pyruvate Kinase Deficiency
PathBank:SMP0120846 Triosephosphate Isomerase Deficiency
PathBank:SMP0120488 Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease
PathBank:SMP0120637 Glycogenosis, Type IB
PathBank:SMP0120645 Glycogenosis, Type IA. Von Gierke Disease
PathBank:SMP0000334 Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency)
PathBank:SMP0000374 Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease
PathBank:SMP0000560 Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1)
PathBank:SMP0087318 Gluconeogenesis
PathBank:SMP0063661 Pyruvate Metabolism
PathBank:SMP0120753 Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency)
PathBank:SMP0120841 Primary Hyperoxaluria II, PH2
PathBank:SMP0120845 Fructose-1,6-diphosphatase Deficiency
PathBank:SMP0120857 Glycogenosis, Type IC
PathBank:SMP0120531 Pyruvate Dehydrogenase Complex Deficiency
PathBank:SMP0120624 Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1)
PathBank:SMP0000196 Leigh Syndrome
PathBank:SMP0000559 Pyruvate Kinase Deficiency
PathBank:SMP0000563 Triosephosphate Isomerase Deficiency
PathBank:SMP0087325 Pyruvate Metabolism
PathBank:SMP0063617 Gluconeogenesis
PathBank:SMP0120708 Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease
PathBank:SMP0120856 Glycogenosis, Type IB
PathBank:SMP0120864 Glycogenosis, Type IA. Von Gierke Disease
PathBank:SMP0120533 Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency)
PathBank:SMP0120622 Primary Hyperoxaluria II, PH2
PathBank:SMP0120626 Fructose-1,6-diphosphatase Deficiency
PathBank:SMP0120638 Glycogenosis, Type IC
PathBank:SMP0000128 Gluconeogenesis
PathBank:SMP0000212 Pyruvate Dehydrogenase Complex Deficiency
PathBank:SMP0000573 Glycogenosis, Type IB
PathBank:SMP0000581 Glycogenosis, Type IA. Von Gierke Disease
PathBank:SMP0087223 Gluconeogenesis
PathBank:SMP0087231 Pyruvate Metabolism
PathBank:SMP0120751 Pyruvate Dehydrogenase Complex Deficiency
PathBank:SMP0120843 Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1)
PathBank:SMP0120506 Leigh Syndrome
PathBank:SMP0120623 Pyruvate Kinase Deficiency
PathBank:SMP0120627 Triosephosphate Isomerase Deficiency
PathBank:SMP0000060 Pyruvate Metabolism
PathBank:SMP0000558 Primary Hyperoxaluria II, PH2
PathBank:SMP0000562 Fructose-1,6-diphosphatase Deficiency
PathBank:SMP0000574 Glycogenosis, Type IC